Hypertrophic Cardiomyopathy....in Search of its Own Identity
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2017, Vol 1, Issue 4
Abstract
Hypertrophic cardiomyopathy is a disease of muscle of heart. The incidence is 0.2% in general population. Only 15% of total patients are being diagnosed and large no of patients are yet to be screen-positive ,about 85%.The motive of this article is to activate medical practioner to diagnose the disease early and prevent the complication ,one of them is sudden death. Incidence of sudden death is about 2% to 4%. In 55% of patients it occurs in autosomal dominant conditions. It occurs due to mutation in one of the nine gene coding protein of cardiac sarcomere. B-MHC, Cardiac Troponin T, Myosin binding protein C, Alpha-Tropomyosin. This will result in cardiac Myocytes Hypertrophy, disturbances in alignment of muscles of heart and disruption of electrical functioning of heart. Its incidence is 33% in close relative of patient.HCM can be asymptomatic. Or it may present as sudden death, syncopal attack, Dysponea or Angina. It is one of the commonest causes of sudden death in all cause mortality. The incidence is 2% to 4%. Sudden death occurs in 30% of patients having HCM. The cause of sudden death is due to ventricular arrythmias, or left ventricular out flow tract obstruction. On clinical examination patient will have Bisferiens pulse, S4 gallop, Ejection systolic murmur at aortic area and murmur of Mitral regurgitation. ESM will be cresendo. Decresendo with normal aortic component os second heart sounds. There will be absence of Ejection systolic click.
Authors and Affiliations
Jayesh V Trivedi
Keywords
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- EP ID EP571555
- DOI 10.26717/BJSTR.2017.01.000388
- Views 150
- Downloads 0
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