Hypoglycemic and Hypolipidemic Activity of Vitis vinifera Leaf Extract in Streptozotocin-Induced Diabetic Rats
Journal Title: International Journal of Ayurveda and Pharmaceutical Chemistry - Year 2018, Vol 0, Issue 0
Abstract
The aim of the study is to analyse the hypoglycemic and hypolipidemic effect of oral administration of methnolic extract of Vitis vinifera (MEVV) on Streptozotocin (STZ) induced diabetic rats. Oral administration of methnolic extract of Vitis vinifera (MEVV) to diabetic rats for 30 days significantly reduced the levels of blood glucose and lipids. The purpose of the study was to investigate the effect of oral administration (400 mg/kg) of the methnolic extract of Vitis vinifera which active ingredients act as hypogycemic and hypolipidemic. The methnolic extract of Vitis vinifera (MEVV) supplementation is useful in controlling the blood glucose level, improves the plasma insulin, lipid metabolism and is beneficial in preventing diabetic complications in experimental diabetic rats; therefore, it could be useful for prevention or early treatment of diabetes mellitus. It also warrants further investigation to isolate and identify the hypogycemic and hypolipidemic principles in this plant so as to elucidate their mode of action.
Authors and Affiliations
Jyoti Singh, Bishnu Kumar
Keywords
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