Hypolipidemic activity of Phyllanthus acidus leaves in Hypercholesterolemic diet-induced hyperlipidemia in rats
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 10
Abstract
Dyslipidemia is characterized by alterations in the lipid parameters. Increase in levels of bad cholesterol and triglycerides in dyslipidemia combined with the reduced levels of HDL predispose to development of various pathological conditions. Dyslipidemia is a well-known risk factor for cardiovascular diseases, acute pancreatitis etc. The phyllanthus genus is abundant in phytochemicals that have lipid lowering properties. Various studies have demonstrated hypolipidemic properties of phyllanthus niruri, Phyllanthus amarus in animals and humans. This study was conducted to evaluate the hypolipidemic potential of the leaves of phyllanthus acidus in hypercholesteromic diet fed rats. Ethanolic extract of leaves of phyllanthus acidus was employed in this study. This study demonstrated hypolipidemic activity of the leaves of phyllanthus acidus in rats. This was however not comparable to standard hypolipidemic drug atorvastatin. Keywords: Lipids, Cholesterol, Hypolipidemia, Atherosclerosis, Metabolic syndrome.
Authors and Affiliations
Singha Binita, Borah Ajoy, Swopna Phukan
Keywords
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