HYPOTHYROIDISM AND AGEING EFFECT ON PULMONARY ARTERY SYSTOLIC PRESSURE
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 3
Abstract
BACKGROUND Hypothyroidism is a cause of pulmonary artery hypertension. Increased BMI also contributes to pulmonary artery hypertension. Increasing age in healthy people is associated with increasing pulmonary artery pressures. MATERIALS AND METHODS We studied 30 subjects of hypothyroidism and 50 healthy controls; mean age was 39.53 ± 14.97 and 38.82 ± 14.65 years respectively. 27 females and 3 males were hypothyroid. 44 females and 6 males were controls. RESULTS Pulmonary artery systolic pressure (PASP) was significantly more in hypothyroid individuals as compared to controls, p-value 0.01, mean PASP in hypothyroid individual was 25.83 ± 6.30 mmHg and in controls it was 23.12 ± 2.97 mmHg. Effect size by r square 0.08. Higher BMI was associated increased PASP in hypothyroid individual. P value 0.01. Effect size by r square 0.11, mean BMI was 24.54 ± 3.95 kg and mean PASP was 25.83 ± 6.30 mmHg. Increasing age was associated with increased PASP in controls. P value 0.01, effect size by r square 0.38; mean age was 38.82 ± 14.65 years and mean PASP was 23.12 ± 2.97 mmHg. CONCLUSION Hypothyroidism is associated with increase in pulmonary artery systolic pressure. Increased BMI of hypothyroid has more effect on increased pulmonary artery systolic pressure than hypothyroidism alone. In healthy subjects, pulmonary artery systolic pressure increases with age.
Authors and Affiliations
Umesh Ramachandra Bilagi, Vinal J. Shah, Krathan Krishna Shetty
Keywords
Related Articles
- EP ID EP609842
- DOI 10.18410/jebmh/2019/28
- Views 104
- Downloads 0
A COMPARATIVE STUDY OF PROXIMAL FEMORAL NAIL AND DYNAMIC HIP SCREW IN THE MANAGEMENT OF INTERTROCHANTERIC FRACTURES OF FEMUR
BACKGROUND Intertrochanteric fractures are commonest fractures especially in the elderly with osteoporotic bones and due to trivial fall. It occurs commonly in patients above 70 years of age. The most commonly used impla...
SUCCESSFUL PREGNANCY IN VOLUMIOUS OVARIAN MUCINOUS CYSTADENOMA
OBJECTIVES: To report the occurrence of a rare case of a huge benign ovarian tumour (Mucinous cystadenoma) with pregnancy. METHODS: The data was collected by historytaking, clinical examination, laboratory investigations...
SQUAMOUS CELL CARCINOMA OF EXTERNAL AUDITORY CANAL: A CASE REPORT
Temporal bone malignancy is a rare entity accounting for 1-6 per 1,000,000. Vast majority of these (20-60%) arise from auricle, more than 25% arise from external auditory canal. Squamous cell carcinoma accounts for 69.2%...
PREVALENCE AND PSYCHOSOCIAL FACTORS OF ALCOHOL USE DISORDER– A PROSPECTIVE STUDY FROM A TERTIARY CARE CENTRE OF ASSAM, INDIA
BACKGROUND Alcohol dependence, also known as alcoholism or alcohol use disorder, is a broad term for any drinking of alcohol that results in many diseases and various psychosocial problems. There are many complications i...
COMPARISON OF AUTOBLOOD GRAFT FIXATION VS. CONJUNCTIVAL GRAFT FIXATION WITH POLYGLACTIN SUTURE IN PRIMARY PTERYGIUM SURGERY
BACKGROUND Pterygium is excessive sub-conjunctival proliferation of fibrovascular tissue or elastotic degeneration of tissue under the epithelium. Pterygium is seen nearly twice as often in men as in women. Ophthalmologi...