Hypothyroidism in pregnancy
Journal Title: Medpulse International Journal of Gynaecology - Year 2018, Vol 5, Issue 3
Abstract
Background: Thyroid physiology is perceptibly modified during normal pregnancy. These alterations take place throughout gestation, help to prepare the maternal thyroid gland to cope with the metabolic demands of pregnancy, are reversible post-partum and the interpretation of these changes can pose a challenge to the treating physician. Aims and Objectives: To determine the current prevalence of thyroid dysfunction in normal pregnancy to study the impact of thyroid dysfunction on maternal and fetal outcome. Materials and Methods: After approval from institutional ethical committee this Prospective study was carried out in the Department of OBGY during 3 months (December 2016 to February 2017) period. All Antenatal cases from December 2016 to February 2017 were studied and undergone TFT; Thyroid profile is being done for all pregnant women as a routine antenatal test in our hospital. The statistical analysis done by SPSS 19 version software and calculated by Chi-square test. Result : Out of the 284 total pregnant women were screened by thyroid disease there was prevalence of sub-clinical hypothyroidism 10% and overt hypothyroidism 4% and overall thyroid dysfunction was 13.60%. The complications like Anemia, Preeclampsia, Abruption, PPH, Mode of Delivery by Caesar was significantly higher in Sub-clinical and Overt hypothyroid patients (p<0.05) as compared to normal patients. The F et al Complications like Preterm birth, IUGR, LBW, Abortions, Still births were significantly (p<0.05); Neonatal Complications like Respiratory distress syndrome*, Hypoglycemia* Hypothermia* were significantly higher (p<0.05) in the babies of woman with sub-clinical or overt hypothyroidism. Conclusion: It can be concluded from our study that The complications like Anemia, Preeclampsia, Abruption, PPH, Mode of Delivery by Caesar was significantly higher in Sub-clinical and Overt hypothyroid patients as compared to normal patients and also the fetal Complications like Preterm birth, IUGR, LBW, Abortions, Still births and Neonatal Complications like Respiratory distress syndrome, Hypoglycemia, Hypothermia were significantly higher in the babies of woman with sub-clinical or overt hypothyroidism.
Authors and Affiliations
Shaikh Badrunnisa, Vinaya Kulkarni, Uttam Bhosale
Keywords
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