IDENTIFICATION OF BIOACTIVE COMPOUNDS AND ANTIBACTERIAL ACTIVITY OF MARINE GASTROPOD CONUS ACHATINUS GMELIN, 1791
Journal Title: International Journal of Advanced Research (IJAR) - Year 2018, Vol 6, Issue 8
Abstract
ThThe aim of the present study is to screen a molluscan gastropod, Conus achatinus to find out the possible bioactive compounds present in the whole body tissues of experimental animal. The antibacterial activity was assayed against ten bacterial pathogens by Disc Diffusion Technique at three different concentrations. The crude methanolic extract showed significant antibacterial activity with minimum inhibitory zone of 2 mm against Pseudomonas aeruginosa and maximum 18 mm against Klebsiella pneumoniae at 100mg/ml concentration. It was further fractionated into four fractions using the different solvent system. Of all the fractions tested, (F2) and) (F3) showed the potent activities. The fraction F2 showed minimum inhibition zone of 9 mm against Pseudomonas aeruginosa and Proteus vulgaris and the maximum of 14 mm against Streptococcus pyogenes and F3 showed the minimum inhibition zone of 12 mm against Klebsiella pneumoniae and 20 mm against Staphylococcus aureus at 100 mg/ml concentration. The GC-MS analysis of the whole body tissue extract of Conus achatinus revealed the presence of alkaloid, amino, nitrogen, aldehyde, alcoholic, sulphur, nitrogen and steroid compounds which might be responsible for the antibacterial activity.
Authors and Affiliations
V. Chandramathi, R. D. Thilaga.
Keywords
Related Articles
- EP ID EP396803
- DOI 10.21474/IJAR01/7598
- Views 48
- Downloads 0
EFFECT OF INJECTION TIMING AND NOZZLE HOLE GEOMETRY ON COMPRESSION IGNITION ENGINE FUELLED WITH THEVETIA PERUVIANA BIODIESEL.
In the present study an experimental work had been carried out to analyze the performance and emission characteristics of various blends of thevetiaperuviana biodiesel by varying injection timings and nozzle hole geometr...
A LITERATURE REVIEW ON LAND USE LAND COVER CHANGES.
The present paper discusses the phenomena of land use and land cover (LULC) which has undergone constant changes over the past few decades due to major variations in the environment caused by anthropogenic and natural fa...
PAVING THE ROAD TO TOBACCO FREE INDIA – COVERED AND UNCOVERED
According to the recently concluded (GATS?India 2016–2017), tobacco use is a major public health challenge in India, with 267 million adults consuming tobacco in different forms. Besides enacting comprehensive tobacco co...
MATHEMATICAL COMMUNICATION PROCESS OF JUNIOR HIGH SCHOOL STUDENTS BASED ON KEIRSEY PERSONALITY TYPE IN SOLVING OPEN GEOMETRY PROBLEMS
The aim of this research is to describe the students\' mathematical communication process of guardian, artist, rational, and idealist personality type in solving the geometry open problems. This research is a descriptive...
A GLANCE AT JOB SATISFACTION THROUGH OCTAPACE CULTURE: AN EMPIRICAL STUDY OF SOFTWARE EMPLOYEES.
Culture is defined as the mind-set, morals and viewpoint of a particular social, cultural or age group. Understanding .organizational culture helps to raise the organizational efficiency and growth. The tool used in this...