Identification of Modified and Unmodified Lipophilic B-Diketones Using Electrospray Ionisation Mass Spectrum (Esi-Ms)
Journal Title: Archives of Organic and Inorganic Chemical Sciences - Year 2018, Vol 2, Issue 1
Abstract
Identification of modified and unmodified lipophilic p-dketone was carried out successfully using positive ion mode of ESI-MS. The ESI-MS spectra were obtained using LC - Agilent 1260 Infinity with MS - Bruker micro OF time of flight MS in mass range of m/z 200-900, capillary voltage 4500V, nebuliser pressure 21.8 psi, dry gas flow 8L/min and dry gas temp 433K. Potassium adduct ion 503.4437m/z was found for the 14,16-Hentriacontanedione (Htd); whereas, the itaconate modified Htd (Ita) gave a confirmatory sodium species 645.5051m/z. The ion 589.4794 m/z was for potassium species of the singly added acrylate modified Htd (Mas). Meanwhile, the doubly added acrylate modified Htd (Mad) formed the potassium adduct ion of 675.5179m/z. However, protonated species for these molecules were not obtained. Electrospray ionization mass spectroscopic technique (ESI- MS) has already been established as a powerful tool in the characterization of small and large molecules [1]. ESI concept was firstly introduced in 1968 by Dole [2]. It is a less energetic ionization technique, where a sample is protonated in gas phase to form cationic species; not radical (as is the case of impact ionization approach), [3] thus causing little or no fragmentation of the parent compound. It is pertinent to make do with ESI-MS because, in some cases, the column in GC is not suitable for detecting very high molecular weight organic compounds. Literature report has it that, ESI-MS method is reliable, robust and much less time consuming than the GC methods [4]. Importantly, ESI-MS is simple, fast, accurate, sensitive and straightforward technique for the analyzing compounds [5,6]. Alternative techniques for analyses of compounds such as NMR need further processing and requisite expertise to enable the identification of a compound.
Authors and Affiliations
Kaana Asemave
Keywords
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- EP ID EP602947
- DOI 10.32474/AOICS.2018.02.000127
- Views 77
- Downloads 0
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