Identification of Modified and Unmodified Lipophilic B-Diketones Using Electrospray Ionisation Mass Spectrum (Esi-Ms)
Journal Title: Archives of Organic and Inorganic Chemical Sciences - Year 2018, Vol 2, Issue 1
Abstract
Identification of modified and unmodified lipophilic p-dketone was carried out successfully using positive ion mode of ESI-MS. The ESI-MS spectra were obtained using LC - Agilent 1260 Infinity with MS - Bruker micro OF time of flight MS in mass range of m/z 200-900, capillary voltage 4500V, nebuliser pressure 21.8 psi, dry gas flow 8L/min and dry gas temp 433K. Potassium adduct ion 503.4437m/z was found for the 14,16-Hentriacontanedione (Htd); whereas, the itaconate modified Htd (Ita) gave a confirmatory sodium species 645.5051m/z. The ion 589.4794 m/z was for potassium species of the singly added acrylate modified Htd (Mas). Meanwhile, the doubly added acrylate modified Htd (Mad) formed the potassium adduct ion of 675.5179m/z. However, protonated species for these molecules were not obtained. Electrospray ionization mass spectroscopic technique (ESI- MS) has already been established as a powerful tool in the characterization of small and large molecules [1]. ESI concept was firstly introduced in 1968 by Dole [2]. It is a less energetic ionization technique, where a sample is protonated in gas phase to form cationic species; not radical (as is the case of impact ionization approach), [3] thus causing little or no fragmentation of the parent compound. It is pertinent to make do with ESI-MS because, in some cases, the column in GC is not suitable for detecting very high molecular weight organic compounds. Literature report has it that, ESI-MS method is reliable, robust and much less time consuming than the GC methods [4]. Importantly, ESI-MS is simple, fast, accurate, sensitive and straightforward technique for the analyzing compounds [5,6]. Alternative techniques for analyses of compounds such as NMR need further processing and requisite expertise to enable the identification of a compound.
Authors and Affiliations
Kaana Asemave
Keywords
Related Articles
- EP ID EP602947
- DOI 10.32474/AOICS.2018.02.000127
- Views 73
- Downloads 0
The Dangers of Lawn Chemicals at Home and Environment-A Problem Dealing Study
The Lawn chemicals are the chemicals which are used in our houses as well as gardens. These chemicals are used to kill the germs, pests, harmful bacteria and viruses. In lawn chemicals, pesticides, herbicides, chemicals,...
Benzotriazole: A Versatile Synthetic Auxiliary
Benzotriazole (BtH) is particularly versatile synthetic auxiliary because of its attractive properties. Benzotriazole can be easily inserted into molecules and equally can also act as a good leaving group. This molecule...
Role of Combinatorial, Medicinal & Biological Chemistry in Drug Discovery Development: An Introduction
Combinatorial chemistry, a new approach for greatly reducing the time for the discovery of newer organic motifs, has been developed over the last few years. Combinatorial chemistry (Figure 1) is a technique...
Biological Studies, Synthesis, Structural, Spectral Characterization and Co-Ordinate Mn (II), Fe (II), Zn (II) (II) Complexes Containing 2-Hydroxy-1- Naphthaldehydeand n,n’-Dimethyl-1,3-Propanediamine
Metal chelates are capable to tolerate their antitumor effects by binding to DNA. DNA binding alters the replication of DNA by inhibiting the growth of the tumor cells, which is the basis of designing new and more effect...
Straw Based Biorefinery
n India energy security and exploring the production of valuable chemicals , which are otherwise mostly imported have become imperative necessity The advantage of abundant availability of paddy and its straws, specifical...