Identification of Stargardt Disease by Comparing with the Healthy Eye
Journal Title: International Journal for Research in Applied Science and Engineering Technology (IJRASET) - Year 2017, Vol 5, Issue 3
Abstract
Stargardt’s disease / Fundus Flavimaculatus (STGD/FF) is a yellow-white spot forms on the outer layer of retina. Which affects RPE Cells (Retinal Pigment Epithelium). Photoreceptor digesion-when light falls on photoreceptor cells it convert light signal into bio-signals. During the conversion process chemical reaction takes places and release bi-product which is called as lipofuscin. The microscopic structure of fundus shows the accumulation of lipofuscin on RPE Cells. RPE Cells are basically vision cells present on the outer layer of the retina. FAF, OCT and AOSLO are the methods to evaluate cone and RPE cell structure in patients with STGD/FF. But using this techniques fundus can be identified only at advanced stage. At this stage the possibility of vision loss is high. So it’s hard to rectify .But by comparing unaffected eye with affected eye using straight edge detection method. In Lab view Software, vision acquisition and vision development module used it is possible to find in initial stage. If the fundus are identified at early stage the patient can be easily rescued from vision loss. Advanced Cell Technology (ACT) is conducting human studies of a retinal degenerative disease treatment derived from human stem cells by placing healthy RPE cells in the retina, researchers believe that they can avoid vision loss at initial stage.
Authors and Affiliations
A. Senthil Kumar, S. Raja, V. Dharpana, V. Geetha, G. Kadambari,
Keywords
Related Articles
- EP ID EP23681
- DOI http://doi.org/10.22214/ijraset.2017.3219
- Views 257
- Downloads 6
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