IL-4 and IL-6 in Bronchial Asthma Does IL-6 Plays More Important Role than IL-4? A Preliminary Study
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 4
Abstract
Summary: Cytokines IL-4, 5, 6 and 13 plays an important role in the pathogenesis & chronicity of bronchial Asthma. Main purpose of the study was to see role of IL-4 & IL-6 in allergic disease. Material & Method: Total 58 cases of bronchial asthma in which 10 cases were having allergic rhinitis and 07 had urticaria, along with 20 healthy controls were taken for study between period of November 13 to December 14. Result: Among 58 patients of asthma, 10 had associated rhinitis and 07 cases had urticaria. Out of 58 cases 58.62% patients were male and 41.38% patients were females. Total 13 patients were children of age group 3-15 year in which males were 23.53% & females were 20.83% . Most common age group was 16-30 years in which 54.16 % were female and 47.05% were male. Total 42 cases (72.41%) were between 3 to 30 years. IL-4 was raised significantly in asthma cases in 25% cases. Similarly, IL-6 was significantly elevated in 48.27% patients of asthma. Thus our study concludes that IL-6 plays more role in pathogenesis of asthma than IL-4. Monoclonal antibody to IL-6 may be tried on this cases`
Authors and Affiliations
Prof Usha
Keywords
Related Articles
- EP ID EP284841
- DOI -
- Views 76
- Downloads 0
Ruptured Amoebic Liver Abscess with Pleuro Pericardial Effusion – A Case Report
Amoebic liver abscess is the most frequent extra intestinal manifestation of Entamoeba histolytica infection. It is caused by the organism which enters the portal system from colon. Very often it ruptures into surroundin...
The Effect of Socio-economic status on the Oral Hygiene of Elementary School Children in the City of Dammam, Saudi Arabia
The purpose of this paper was to determine the status of the oral health of children compared to the socioeconomic status (SES) of the parents in the city of Dammam, Saudi Arabia. Three schools were targeted based on the...
A Prospective study on outcome following mechanical ventilation among children in a tertiary care hospital
Background: Mechanical ventilation (MV) in paediatric intensive care unit is a major therapeutic modality especially among children with respiratory distress and apnoea. Adequate sedation, frequent vitals monitoring, uri...
Review on Chronic Kidney Disease: Its Risk Factors and Treatment
Chronic kidney disease (CKD) is a life threatening condition characterized by progressive and irreversible loss of renal function. CKD is a precursor to end-stage renal disease, is associated with increased risk of morbi...
A Clinical Study of Programmed Labour and its Maternal and Fetal Outcome
Programmed labor aims at reducing the duration of labor, labor pain and incidence of cesarean section with improved maternal and neonatal outcome. The aim of the present study was to evaluate the efficacy of providing ob...