IMAGING OF INTRACRANIAL SPACE OCCUPYING LESIONS- A PROSPECTIVE STUDY IN A TERTIARY CARE CENTRE- GGH, KAKINADA, A.P.
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 11
Abstract
BACKGROUND The high morbidity and mortality associated with ICSOLs necessitates their early diagnosis so as to plan the required intervention. An analysis of 50 cases of Intracranial Space Occupying Lesions (ICSOL) including neoplastic and non-neoplastic masses diagnosed and treated at GGH, Kakinada, over a period of one year is presented. CT scan and MRI were used for the diagnosis. MATERIALS AND METHODS In this prospective cohort study, 50 patients with ICSOL were studied predominantly by MRI and also by CT and MRS (wherever necessary). Imaging findings were evaluated, tabulated and correlated with histopathological findings and also clinical findings (wherever available). The findings were statistically analysed. RESULTS Most patients were in age range of 50-60 years. Male:female ratio was 2:3. Most common presenting symptom was headache associated with vomiting. Predominantly, solitary lesions were present in 47 patients (94%) and multiple lesions in three patients (6%). 39 cases were supratentorial, 10 cases were infratentorial and one lesion was both supra and infratentorial in location. 40 patients were having neoplastic lesions (80%) and 10 had non-neoplastic lesions (20%). In our study, meningiomas were the most common neoplastic lesion while among non-neoplastic lesions, arachnoid cysts were the most common. Of the neoplastic cases, 12 cases (30%) were malignant and 28 (70%) cases were benign mass effect was the most common associated imaging finding. For neoplastic lesions, the imaging sensitivity was 92.5%, specificity was 70%, accuracy was 88%, positive predictive value was 92.5% and negative predictive value was 70%. While for the non-neoplastic lesions, imaging sensitivity was 70%, specificity was 92.5% and accuracy was 88%. CONCLUSION Neuroimaging in combination with clinical findings can be helpful in early diagnosis and localisation of ICSOL and for proper management of the patient. The neurosurgeon, neuroradiologist and neuropathologist form a triad that is essential for diagnosis, management and follow up of these cases.
Authors and Affiliations
Radha Rani Kaki, Bonthu Anuradha, Bomidi Sudha Rani, Karri Sambasiva Rao, Pasam Kusumalatha, Kommana Satyasuneetha
Keywords
Related Articles
- EP ID EP214005
- DOI 10.18410/jebmh/2017/120
- Views 99
- Downloads 0
A STUDY OF PELVIC PAIN IN WOMEN
BACKGROUND Pelvic pain is not an uncommon complaint in women and its diagnosis and management can be taxing at times. Acute pelvic pain is an emergency and requires prompt and selective investigations to deal with the co...
AN OPEN-LABEL, SINGLE-TREATMENT, SINGLE-PERIOD, SINGLE DOSE, CLINICAL PHASE 1 STUDY TO ASSESS THE SAFETY AND TOLERABILITY OF TETANUS VACCINE IN HEALTHY, ADULT SUBJECTS IN INDIA
BACKGROUND Tetanus toxoid vaccine has always been an indelible constituent of the Universal Immunization Programme in India. Besides being given to pregnant women in two doses, it used to be given in children at the ages...
BURDEN AND QUALITY OF LIFE– A COMPARISON OF THOSE CARING FOR PSYCHIATRICALLY ILL AND MEDICALLY ILL
BACKGROUND Despite epidemiological transitions, communicable diseases are widely prevalent world over, concomitantly non-communicable diseases are also on the rise. Mental and behavioural disorders account for 12% of the...
PLACENTAL SIZE AND PERINATAL OUTCOMES
BACKGROUND: The human placenta, a transient organ or pregnancy provides information about fetal well-being and pregnancy outcome. AIMS: To study the placental ultrasound characters in relation to perinatal outcomes. SETT...
KNOWLEDGE GAINED FROM A BRIEF SIMULATION-BASED TRAINING ON BASIC NEONATAL RESUSCITATION AMONG NEWLY APPOINTED NURSES - A RETROSPECTIVE STUDY
BACKGROUND Assessing the need of resuscitation and ventilation with bag and mask if needed soon after birth to initiate breathing can decrease neonatal mortality and morbidity. The knowledge on basic neonatal resuscitati...