Immune Thrombocytopenia after Allogeneic Stem Cell Transplantation: Case Report and Brief Overview of Treatment Strategies
Journal Title: Journal of Hematology and Oncology Research - Year 2016, Vol 2, Issue 3
Abstract
Immune thrombocytopenia (ITP) is a rare but well-recognized post-allogeneic hematopoietic stem cell transplant (HSCT) autoimmune complication for which a standard treatment approach is lacking. Herein we report on an adult patient affected by high-risk acute myeloid leukemia (AML) who developed a post-HSCT ITP. Due to the refractoriness to first-line therapies the patient underwent the thrombopoietin (TPO) mimetic Eltrombopag obtaining the ITP resolution. We also discuss the clinical course of ITP in post-HSCT setting and pros and cons of different therapeutic strategies, focusing on the emerging role of TPO mimetics.
Authors and Affiliations
Isacco Ferrarini, Gloria Turri, Dino Veneri, Cristina Tecchio, Achille Ambrosetti
Keywords
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- EP ID EP250429
- DOI 10.14302/issn.2372-6601.jhor-16-1330
- Views 187
- Downloads 0
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