Immunohistochemical Association of HER-2 /Neuimmunoprotein with HistomorphologicalVariables in Patients in Gastric Carcinoma.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 4
Abstract
Gastric tumour is the fourth most common cancer and the second leading cause of death due to cancer worldwide. Gastric cancer is more common in male than in female in the ratio of 2:1. It is a disease of elderly. The histological and morphological types of gastric carcinomas are highly variable and may not correlate well with the prognosis of the patients.Molecular markers are vital in determining the disease progression and hence disease outcome, survival and prognosis.The objective of the study was to correlate the association of HER-2/Neu in Gastric adenocarcinoma with histomorphological variables. This was a retrospective study carried out in our institution on 100 cases. There was a significant association between HER-2 Neu overexpression and histological grading of adenocarcinoma.
Authors and Affiliations
Dr. Lokesh Kumar, Dr. Geetha Lakshmi . S
Keywords
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