Immunoinformatics: Implications on Reverse Vaccinology
Journal Title: UNKNOWN - Year 2017, Vol 3, Issue 1
Abstract
One area in which immunological studies have had most immediate and successful application is in the field of vaccination. Vaccines represent one of the greatest interventions in modern medicine [1]. Ever since Edward Jenner’s first use of a vaccine against smallpox in 1796, the use of vaccines has become indispensable to the eradication of disease [2]. Then, Scientific progress has driven vaccine development from live attenuated and inactivated vaccines to purified recombinant one. The recent advances in bioinformatics, proteomics, immunoinformatics, structural biology and others have led to vaccinomics and reverse vaccinology as novel approaches for a generation of new vaccines [3]. Reverse vaccinology relies on the genomic information to identify relevant protein antigens and the design of algorithm for mapping potential B and T cell epitopes for diagnostic or vaccine purposes [4].
Authors and Affiliations
Mawadda Abd_Elraheem Awad _Elkareem, Mohammed Ahmed Salih
Keywords
Related Articles
- EP ID EP356487
- DOI 10.4172/2469- 9756.1000127
- Views 58
- Downloads 0
Commentary on the Development and Application of Chitosan in Immunochemistry
Chitosan has attracted much interest due to its special physical and chemical properties related to immunochemistry. The aim of this commentary is to appraise chitosan as an attractive functional polymer for medicine app...
Varicella Zoster Acute Retinal Necrosis: A Case Report and Brief Review of the Literature
A 50-year-old woman with well controlled hypertension, hyperlipidemia, plaque psoriasis, exercise induced asthma, and migraine headaches presented with a few days of right eye pain. She was diagnosed with a migraine head...
Immunoinformatics: Implications on Reverse Vaccinology
One area in which immunological studies have had most immediate and successful application is in the field of vaccination. Vaccines represent one of the greatest interventions in modern medicine [1]. Ever since Edward Je...
Breed, Age and Sex Wise-Distribution of Parvoviral Enteritis Among Canines Based on Loop-Mediated Isothermal Amplification Assay
The present study was undertaken to detect parvoviral infection among various breeds, age and sex of dogs using Loop-mediated isothermal Amplification (LAMP) assay. A total of 54 faecal samples collected from diarrheic d...