Impact of Achyranthes aspera L. on Protein Profile in Impaired Wound Models
Journal Title: Indo Global Journal of Pharmaceutical Sciences - Year 2011, Vol 1, Issue 1
Abstract
In the present study, comparative protein profile of granulation tissues of burn, diabetic and immunocompromised wounds treated with 5.0% (w/w) ointment of methanol extract of Achyranthes aspera was undertaken. Granulation tissue of A. aspera treated group showed expression of a protein with molecular weight 69.4 kD in burn wound and proteins ranging from high, medium and low molecular weight (61.0, 55.0 and 31.5kD) in diabetic and immunocompromised wounds. A. aspera treatment induced expression of a particular protein of molecular weight 31.5 kD in both diabetic and immunocompromised wound models, signifying that this particular protein might play a key role in A. aspera mediated wound healing in these two models. © 2011 IGJPS. All rights reserved
Authors and Affiliations
Keywords
Related Articles
- EP ID EP124573
- DOI -
- Views 74
- Downloads 0
Synthesis, Urease Inhibition, Antimicrobial and Antioxidant Studies of 3,4,5-Trihydroxy Benzoic Acid Derivatives
A series of fourteen 3, 4, 5-trihydroxy benzoic acid were synthesized by schematic route shown in scheme 1 and characterized by spectroscopic analysis. All the newly synthesized derivatives were evaluated for their antim...
Immobilization Effect of Traditional Contraceptive Plants on Human Sperm
The aim of the present study is to support the ethno botanical knowledge of contraception with evidence by evaluating the activity of aqueous seed extracts of selected traditional contraceptive plant species. In this stu...
Patents, Health Policy and Access to Medicines
Intellectual property rights are the rights given to person over the creation of their inventions. They usually give the creator as exclusive right over the use of his/her invention for certain period of time, usually 20...
Antioxidant Potential of Some Under-Utilized Fruits
To identify their potential sources extracts of some fruits and their different parts were studied for total phenolic contents (TPC), antioxidant (AOA) and free radical scavenging activities (FRSA). Phenols have profound...
A Review: Development & Validation of HPLC Method for the Determination of Esomeprazole in Pharmaceuticals