Impact of Body Mass Index on Vascular Calcifcation and Pericardial Fat Volume Among Patients with Suspected Coronary Artery Disease
Journal Title: Sultan Qaboos University Medical Journal - Year 2016, Vol 16, Issue 3
Abstract
Objectives: Tis study aimed to assess the effect of body mass index (BMI) on the relationship between pericardial fat volume (PFV), aortic root calcifcation (ARC) and coronary artery calcifcation (CAC) among patients with suspected coronary artery disease (CAD). Methods: Tis cross-sectional study took place between January and December 2014 at the Kufa University Teaching Hospital, Najaf, Iraq. A total of 130 consecutive patients with an intermediate pretest probability of ischaemic heart disease who underwent 64-slice multidetector computed tomography (CT) angiography during the study period were recruited. Of these, 111 were included in the study and divided into groups according to BMI. Imaging markers were measured on CT angiography. Results: A total of 28 patients were obese, while 42 and 41 were overweight and normal weight, respectively. Te median PFV, CAC and ARC was 109 cm3 (interquartile range [IQR]: 52–176 cm3), 0 Agatston score (IQR: 0–52 Agatston score) and 0 Agatston score (IQR: 0–15 Agatston score), respectively, in the normal weight group in comparison to 79 cm3 (IQR: 43–138 cm3), 0 Agatston score (IQR: 0–54 Agatston score) and 0 Agatston score (IQR: 0–0 Agatston score), respectively, in the obese group. Signifcant correlations were observed between PFV and CAC (r2 = 0.22; P = 0.002) and ARC and CAC (r2 = 0.37; P <0.001) in the normal weight group. However, no signifcant correlations were observed for obese and overweight patients. Conclusion: Tese fndings indicate that BMI may not be an accurate tool for measuring adiposity or assessing subclinical coronary atherosclerosis in patients with suspected CAD.
Authors and Affiliations
Hussein Nafakhi| Departments of Internal Medicine, Faculty of Medicine, University of Kufa, Najaf, Iraq, Abdulameer Al-Mosawi| Departments of Radiology, Faculty of Medicine, University of Kufa, Najaf, Iraq, Hayder Elwali| Departments of Radiology, Faculty of Medicine, University of Kufa, Najaf, Iraq, Hasan Al-Nafakh| Departments of Radiology, Faculty of Medicine, University of Kufa, Najaf, Iraq, Raad Tawfeq| Department of Radiology, Almustansyria University, Baghdad, Iraq, Ahmed Nafakhi| Department of Clinical Pharmacy, Najaf Health Bureau, Najaf, Iraq
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