Impact of Botulinum Toxin Consultation Shutdown Due to the Covid-19 Pandemic on Spasticity Treatment: A Review of the Literature

Journal Title: Advances in Clinical Toxicology - Year 2021, Vol 6, Issue 2

Abstract

Introduction: The COVID-19 pandemic has imposed an additional pressure on health systems worldwide, creating an increased challenge to chronic patient management due to consultation shutdown. Spastic patients were especially vulnerable to inadequate care. This review aims to describe the impact of botulinum toxin (BT) consultation interruption due to the COVID-19 pandemic on spasticity treatment. Methods: A literature search was conducted in the database of Medline, PubMed, Embase, Google Scholar and Scopus. Keywords for the search included “COVID-19” AND “Botulinum Toxin” AND “Spasticity”. Results: A total of 6 studies reporting the impact of BT consultation suspension on spasticity due to the COVID-19 pandemic met inclusion criteria. All studies were observational and included a small sample. Consultation interruption was variable between studies and ranged from 36-75 days, originating a mean treatment delay of 23-129 days due to re-scheduling difficulties. The majority (72-93%) of patients in all studies perceived worsening of spasticity with BT consultation suspension. Effects seem to be worse with longer treatment delays and concerning the mobility and passive function treatment objectives. Some studies reported a worse quality of life in patients with BT treatment delay whilst others did not find this association.

Authors and Affiliations

Ferreira EF*, Portugal D, Silva N, Peixoto C, Prates L and Neves AF

Keywords

Related Articles

Biochemical Effect of Artemisin-based Combination Therapy (ACT) Antimalarial Drugs on Enzymatic Antioxidants in Pregnancy

This study was undertaken to determine the effect of artemisin-based combination therapy (ACT) on Plasma enzymatic antioxidants in pregnant women with malaria. Seventy-five (75) consenting pregnant subjects (25malarial...

Opposite Effects of Metformin against Non-Alcoholic Fatty Liver Disease, Depend on Steatosis Grade

Currently, as there are no standardized treatment regimen for non-alcoholic fatty liver disease (NAFLD) and the assumption of insulin resistance involved in NAFLD, so, the effectiveness of medicines of type 2 diabetes m...

A Comparative Study on the Properties of Mangrove and Non - Mangrove Soils of Sundarbans, West Bengal, India

Substrate characteristics are important determining factors that control the community structure and growth of mangrove ecosystem. On the other hand, occurrence of mangrove vegetation may also exert considerable influen...

Carbon Nanotubes-Doxorubicin Conjugates Molecular Dynamics and Bio-inspired Approaches for Clinical Toxicology

Doxorubicin as a therapeutic drug is used in several human pathologies related to cancer. It has however some side effects that needs to be understood and controlled. This article discusses some applications using singl...

COVID-19 Implication by Physical Interaction of Artificial fog on Respiratory Aerosols

Background: Artificial fog consists of small liquid aerosols suspended in air which reduce visibility and reflect light. Artificial fog is used in the film, television, and live entertainment industries to enhance lighti...

Download PDF file
  • EP ID EP751779
  • DOI 10.23880/act-16000212
  • Views 1
  • Downloads 0

How To Cite

Ferreira EF*, Portugal D, Silva N, Peixoto C, Prates L and Neves AF (2021). Impact of Botulinum Toxin Consultation Shutdown Due to the Covid-19 Pandemic on Spasticity Treatment: A Review of the Literature. Advances in Clinical Toxicology, 6(2), -. https://europub.co.uk/articles/-A-751779