Impact of Diabetes on Optic Nerve and Optic Nerve Sheath Measurement: MRI based study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 7
Abstract
The aim of this study was to study the impact of the diabetic in optic nerve measurement by using magnetic resonance imaging (MRI). MR images closed magnet, (Signa high definition (HD) with magnetic field strength1.5T (General Electric (GE), USA) was used. The axial T2-weighted turbo spin-echo fat-suppressed sequence was used to measure optic nerve sheath diameter (ONSD) and optic nerve diameter (OND). The sample was divided into two groups: Group 1 including one hundred was considered as control, males were 45% and females were 55%. Their ages were between (18-80) years old with mean 39.46 years±15.81.Group 2 including fifty diabetic patients. MRI exams were done for right and left optic nerves and optic sheath. Males were 52% and female were 48%. Their age ranged from 23-84 years old with mean age of 59.4 years ± 13.7. The study revealed a reference values measured in axial MRIs for OND was 3.05±0.23 for the right side and 3.05 ±0.22 for the left side , The mean ONSD in the diabetic group was 5.03 ± 0.53mm for the right, and 5.08±0.48 for the left ,and showed no difference from that in control group p = 0.795 and 0.742 respectively. The study indicated that MR OND measurements in diabetic patients differ from the reference values that have been read from normal in the control group .There is significant deference between measurement done for the optic nerves diameters between diabetic and control group. p=0.000.linear relationship between the duration of diabetic with right and left optic nerve diameter measurements was found. The study concluded that diabetes affected the OND and it was significantly decreased than that in healthy controls. New equations were established for the prediction of the OND changes in patients with known duration of diabetics for both right and left optic nerves
Authors and Affiliations
Sahar Abd Elwahed Osman, Caroline Edward Ayad, Duha Abdu Mohammed Abdu
Keywords
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- EP ID EP377275
- DOI 10.9790/0853-1707044044.
- Views 62
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