Impact of dietary glutathione on hematological indices in rats poisoned with hexavalent chromium
Journal Title: Journal of Applied and Natural Science - Year 2013, Vol 5, Issue 1
Abstract
The effects of dietary glutathione against chromium induced hematological indices were studied in rats, Rattus rattus albino. Supplementation of glutahione to the diet of chromium fed rats, elevated significantly percent hemoglobin (40.4%), number of red blood corpuscles (48.7%), plasma corpuscular volume (43.4%) and mean corpuscular volume (37.1%) which were inhibited in chromium poisoned rats. However, no marked elevation was noticed in number of white blood corpuscles and total proteins. Intake of glutahione checked the accumulation of glucose, cholesterol, tryglcerides, phospholipids and bilirubin in chromium treated rats. Chromium intoxication significantly increased the activities of transaminases (p<0.001) and dehydrogenases (p<0.01/p<0.001) which declined by supplementation of gltathione which also restored the chromium inhibited activity of alkaline and acid phosphatase. Specific reasons for these pharmacoticological aspects of glutathione have also been discussed.
Authors and Affiliations
Ajay Kumar, Alok Kumar
Keywords
Related Articles
- EP ID EP87658
- DOI 10.31018/jans.v5i1.309
- Views 132
- Downloads 0
Efficacy of anthranilic insecticide E2Y45 20 SC (Chlorantraniliprole) against Plutella xylostella L. in cabbage, Brassica oleracea var. capitata
Experiments were conducted at farmer’s cabbage fields to evaluate the bioefficacy of anthranilic insecticide i.e. E2Y45 20 SC (Chlorantraniliprole) having novel mode of action against the diamondback moth Plutella xylost...
Effect of integrated nitrogen management on NPK uptake in basmati rice (Oryza sativa L.)
A field experiment entitled NPK uptake influenced by integrated nitrogen management in basmati rice (Oryza sativa L.) was conducted at Punjab Agricultural University, Ludhiana during kharif 2010. The experiment was condu...
Effect of dietary supplementation of marigold oleoresin on growth, survival and total muscle carotenoid of Koi carp, Cyprinus carpio L.
The experiment was conducted to evaluate the effect of dietary supplementation of carotenoid (marigold oleoresin) on growth, survival and total body carotenoid of Koi carp (Cyprinus carpio). The experiment was carried ou...
Infection status of Clinostomum complanatum (Rudolphi, 1819) metacercaria from Channa punctatus of Meerut District
Metacercaria Clinostomum complanatum is a digenetic trematode, which is mainly found in fresh water fishes. Present communication deals with the infection status of C. complanatum in C. punctatus of Meerut district, whic...
Bacterial flora associated with the selected life stages and organs of farmed giant freshwater prawn Macrobrachium rosenbergii (de Man)
Bacteria associated with different life stages of giant freshwater prawn (Macrobrachium rosenbergii de Man) were analyzed. The gill, hepatopancreas, haemolymph of brood and juveniles as well as the egg, larvae and larval...