Impact of Early Nasal Obstruction in Histological Development of and Physiological State
Journal Title: International Journal of Oral and Craniofacial Science - Year 2015, Vol 1, Issue 2
Abstract
Introduction: Nasal obstruction is a risk factor in sleep-disordered breathing with a negative impact on the quality of life in humans. Objective: In this study we determined whether histological development of olfactory bulb development could be influenced by an early temporary (3 d) nasal obstruction associated with physiological state. Methods: The rats were killed at specific time points after surgery. Plasma samples were taken for biochemical analyses, and histological measurements were performed. Shortly after nasal obstruction, the volumes of external plexiform (CPE), internal plexiform (CGI), and granule cell (CGr) was measured in both sexes of test rats compared with controls. Results and Conclusion: Reversible nasal obstruction was further associated with reduced dimensions of the volumes of CPE (male: 55%; female: 37%), CGI (male: 49%; female: 34%) and CGr (male: 70%; female: 47%). Basal corticosterone levels had increased in female rats, however, we observed the lower level of thyroid hormone, especially in male experimental group. We conclude that a 3-d nasal obstruction period in young rats leads to long-term hormonal changes was associated in modification of histological structural of olfactory bulb.
Authors and Affiliations
Padzys Guy Stéphane, Martrette Jean Marc, Trabalon Marie
Keywords
Related Articles
- EP ID EP335828
- DOI 10.17352/2455-4634.000007
- Views 90
- Downloads 0
Cutting bone with drills, burs, lasers and piezotomes: A comprehensive systematic review and recommendations for the clinician
Background: New tools for bone-cutting were introduced to oral and maxillofacial surgery in the last decade, such as lasers and piezotomes. Purpose: to evaluate most recent evidence, when surgical procedures performed wi...
Dental Caries Status and Relevant Factors in Children with Primary Nephrotic Syndrome in National Children Hospital, Vietnam
Objectives: 1) To give a description for dental caries status of children suffering primary nephrotic syndrome in National Children’s Hospital 2016-2017; 2) to provide a comment on mentioned-above children dental caries...
A Comparative Study of the Efficiency of two Different Glass Ionomer Using ART Technique in a Group of Egyptian Children with Autistic Spectrum Disorder
Aim: The aim of the study was to evaluate and compare the effect of conventional glass ionomer cement and Nano-glass ionomer using atraumatic restorative technique (ART) in a group of Egyptian autistic children. Materia...
Evaluation of Head Position in Static and Dynamic Three-Dimensional Imaging: a review of the Literature
Background: The interest in three-dimensional imaging in orthognathic treatment planning has been growing, especially for evaluation of the natural head position. Several three-dimensional devices are available on the ma...
Rehabilitation of Surgically Resected Soft Palate with Interim Velopharyngeal Obturator
Rehabilitation of surgical resection defects is always a challenging clinical scenario. These defects pose a major physiological and psychological threat not only to the patients, but to the entire family. A multidiscipl...