Impact of Laparoscopic Ovarian Drilling (LOD) on Ovarian Reserve and Ovarian Stromal Blood Flow Using Two-Dimensional (2D) Power Doppler in Anovulatory Women with Polycystic Ovary Syndrome (PCOS)
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2018, Vol 71, Issue 4
Abstract
<span>Aim of the Study: </span><span>this study aimed to determine the effect of LOD on ovarian reserve and ovarian stromal blood flow changes, by using Two-Dimensional (2D) Power Doppler Ultrasongraphy in anovulatory women with Polycystic Ovary Syndrome (PCOS) and whether this could explain the mechanism of action of LOD. </span><span>Patients and methods</span><span>: this study was conducted in the Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Al-Hussein University Hospital, El-Sayed Galal Hospital and EL-Sheikh Zayed Especialized Hospital in the period between November 2016 and February 2018. This study included 30 anovulatory polycystic ovary women with clomiphene citrate (CC)-resistant and 30 fertile women as the control group. Laparoscopic ovarian drilling was done. Serum levels of hormonal profile were measured (AMH, LH, FSH, LH/FSH ratio and total testosterone), ovarian stromal blood flow Doppler indices (RI and PI) and occurrence of ovulation or pregnancy. </span><span>Result: </span><span>in this study we reported our findings regarding the effects of LOD on AMH, hormonal profile and ovarian stromal blood flow in women with PCOS with clomiphene resistance. These results suggested that the measurement of AMH, LH, LH/FSH ratio, total testosterone, ovarian volume and ovarian stromal blood flow by Doppler were in discrimination of PCOS from potentially normal women. The data in our study suggested that there were no significant differences as regard AMH, hormonal profile except total testosterone, ultrasound ovarian findings and ovarian stromal blood flow before and after LOD, but there were significant differences as regard total testosterone before and after LOD. Also, there was good predictive value for AMH after LOD for ovulation and clinical pregnancy. </span> <span>Conclusion: </span><span>measuring AMH for anovulatory women with PCOS undergoing LOD may be a useful tool in evaluating the outcome of LOD, but ovarian stromal blood flow 2D Doppler indices did not show significant changes predicting ovulation or pregnancy rate after LOD.<br /> </span>
Authors and Affiliations
Eman Helal
Keywords
Related Articles
- EP ID EP583922
- DOI -
- Views 60
- Downloads 0
The Role of Topical Nasal Steroid in Treatment of Otitis Media with Effusion in Children: Systematic Review
<strong>Background: </strong>otitis media with effusion is common in children and the treatment is still controversial issue. <strong>Objective</strong>: this study aimed to evaluate the role of topical nasal steroid in...
Attitude and practice regarding the use of multivitamins for hair fall: Cross sectional study in Saudi Arabia
Background: Despite the lack of evidence which support the hypothesis that usage of multivitamins is effective in preventing hair fall, their use is still prevailing. Although recent studies demonstrated interference of...
Assessment of the Knowledge of Gastroesophageal Reflux Disease among The Saudi Population of Altaif City
Background: gastroesophageal reflux disease (GERD) ranks as one of the most common gastrointestinal disorders. Up to this date, no studies examined the level of health knowledge of Saudi population about GERD.
Awareness of Systemic Lupus Erythematosus amongStudents in King Faisal University
<strong>Background</strong>: Systemic lupus erythematosus (SLE) is an autoimmune disease where the body's immune system mistakenly attacks healthy tissue. It can affect the skin, joints, kidneys, brain, and other organs....
Symptoms and Prevalence of Constipation among Adult Population of Riyadh City: An Internet Based Survey
<strong>Background:</strong> Constipation is commonly encountered in clinical practice. The global population is witnessing a rapid increase in its occurrence. <strong>Objectives: </strong>Since there is paucity of data...