Impact of LEP and LEPR gene polymorphisms on functional traits in Polish Holstein-Friesian cattle

Journal Title: Animal Science Papers and Reports - Year 2010, Vol 28, Issue 2

Abstract

Five single nucleotide polymorphisms in leptin and leptin receptor genes were analysed for their possible impact on estimating breeding values for somatic cell count score (SCS) in milk, longevity and reproductive traits. Used were 309 active Polish Holstein-Friesian bulls. The LEP-C(-963)T, LEP-Y7F, LEP-R25C, LEP-A80V, and LEPR-T945M genotypes were identified using the PCRRFLP method. For linked leptin mutations, the additional haplotype analysis was performed. The results obtained suggest that three polymorphisms of bovine LEP gene may be associated with nonreturn rate in cows. The most significant effect was found for LEP-A80V. Moreover, the LEPRT945M mutation seemed to be related to the age at first insemination.

Authors and Affiliations

Jolanta Komisarek

Keywords

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  • EP ID EP71426
  • DOI -
  • Views 93
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How To Cite

Jolanta Komisarek (2010). Impact of LEP and LEPR gene polymorphisms on functional traits in Polish Holstein-Friesian cattle. Animal Science Papers and Reports, 28(2), 133-142. https://europub.co.uk/articles/-A-71426