Impaired Fasting Glucose in Omani Adults with no Family History of Type 2 Diabetes
Journal Title: Sultan Qaboos University Medical Journal - Year 2014, Vol 14, Issue 2
Abstract
Objectives: Te aim of this study was to estimate the prevalence of impaired fasting glucose (IFG) among Omani adults with no family history (FH) of diabetes and to investigate the factors behind the risk of developing type 2 diabetes (T2D), while excluding a FH of diabetes. Methods: A total of 1,182 Omani adults, aged ≥40 years, visited the Family Medicine & Community Health Clinic at Sultan Qaboos University Hospital, Oman, on days other than the Diabetes Clinic days, from July 2010 to July 2011. Te subjects were interviewed and asked if they had T2D or a FH of T2D. Results: Only 191 (16%) reported no personal history of T2D or FH of the disease. Of these, anthropometric and biochemical data was complete in 159 subjects. Of these a total of 42 (26%) had IFG according to the American Diabetes Association criteria. Body mass index, fasting insulin, haemoglobin A 1C and blood pressure (BP), were signifcantly higher among individuals with IFG (P <0.01, P <0.05, P <0.01 and P <0.01, respectively). In addition, fasting insulin, BP and serum lipid profle were correlated with obesity indices (P <0.05). Obesity indices were strongly associated with the risk of IFG among Omanis, with waist circumference being the strongest predictor. Conclusion: Despite claiming no FH of diabetes, a large number of Omani adults in this study had a high risk of developing diabetes. Tis is possibly due to environmental factors and endogamy. Te high prevalence of obesity combined with genetically susceptible individuals is a warning that diabetes could be a future epidemic in Oman.
Authors and Affiliations
Sawsan Al-Sinani| Departments of Biochemistry,College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman, Mohammed Al-Shafaee| Departments of Family Medicine & Public Health, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman, Ali Al-Mamari| Departments of Medicine, Sultan Qaboos University Hospital, Muscat, Oman, Nicolas Woodhouse| Departments of Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, Muscut Oman, Omayma El-Shafe| Departments of Medicine, Sultan Qaboos University Hospital, Muscat, Oman, Mohammed O. Hassan| Departments of Physiology, College of Medicine & Health Sciences, Sultan Qaboos University, Muscut, Oman, Said Al-Yahyaee| Departments of Genetics, College of Medicine & Health Sciences, Sultan Qaboos University, Muscut, Oman, Sulayma Albarwani| Departments of Physiology, College of Medicine & Health Sciences, Sultan Qaboos University, Muscut, Oman, Deepali Jaju| Departments of Clinical Physiology, Sultan Qaboos University Hospital, Muscat, Oman, Khamis Al-Hashmi| Departments of Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, Muscut, Oman, Mohammed Al-Abri| Departments of Clinical Physiology, Sultan Qaboos University Hospital, Muscat, Oman, Syed Rizvi| Departments of Family Medicine & Public Health, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman, Riad Bayoumi| Departments of Biochemistry,College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman
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