IMPORTANCE OF NON-DIPPING PATTERN IN CHRONIC KIDNEY DISEASE PATIENTS
Journal Title: IJAR-Indian Journal of Applied Research - Year 2019, Vol 9, Issue 7
Abstract
INTRODUCTION: Hypertension was prevalent in 80 to 90% of patients with chronic kidney disease (CKD), Hypertension was widely known to accelerate the progression of CKD and increase the risk of cardiovascular (CV) events. In essential hypertension, it was observed that 24hr ambulatory BP and a non-dipping profile were closely associated with increased target-organ damage and a worsened CV outcome than clinic BP. OBJECTIVE: The purpose of this study was to evaluate the relation between non dipping pattern, traditional risk factors such as age, gender, cholesterol, asymptomatic atherosclerosis markers (LVMI, Carotid IMT, ABI) and cardiovascular mortality in CKD patients. METHODOLOGY: Patients attending hemodialysis unit and the outpatient department of the Osmania General Hospital were formed as the material of study. RESULTS: According to the Sleep /Awake BP ratio> 0.9 in their ambulatory BP recordings; The percentage of non dipping pattern was observed in 72% and the remaining 28% had dipping phenomenon. The estimated glomerular filtration rate (eGFR) calculated by Modification of diet in renal disease study (MDRD) equation has ranged around 4.8 to 77 ml/mim/1.73m2 and was negatively correlated with sleep/awake BP ratio. The percentage of diabetes was observed to be higher in the non-dippers. The non-dipping phenomenon was significantly associated with asymptomatic atherosclerosis markers (LVMI, Carotid IMT, and ABI). There was a high prevalence of CV events (1 in dipper and 17 in nondippers) and CV related deaths (1 in dipper and 9 in non-dippers) in non dippers.
Authors and Affiliations
K Naga Jyothi, S Manisha, Kiran mayi
Keywords
Related Articles
- EP ID EP612701
- DOI -
- Views 44
- Downloads 0
A Rare Case of Disseminated Cysticercosis
This is the report of a case of disseminated cysticercosis,with simultaneous involvement of the brain,muscles and subcutaneous tissues.Such an extensive involvement of cysticercosis is extremely rare and has been reporte...
Nasolabial flap As A Reconstructive Option for the Management of Submucous Fibrosis- A Clinical Study
BACKGROUND: Oral submucous fibrosis is a peculiar ,progressive , inciduous, irreversible chron-ic de bilitating disease associated with restricted mouth opening, blanching and stiffness of mucosa, burning sensation in mo...
QR-Based OTP Authentication to Prevent Keylogging
Keylogging is an activity of capturing users’ keyboard strokes and records the activity of a computer user in a covert manner using keylogger hardware and software. The keyloggers secretly monitors and log all keystrokes...
AN ANALYTICAL STUDY OF THE IMPACT OF ONLINE SHOPPING ON CUSTOMER SATISFACTION
Online shopping in India has increased signicantly. Those days are gone when people used to visit the stores for buying their necessary products. Now, there are various e-commerce websites like Amazon, Flipkart etc. tha...
SECONDARY TRAUMATIC STRESS AMONG NURSES IN A TERTIARY CARE HOSPITAL
Nursing is a highly stressful profession, because nurses provide help and support for people suffering from trauma, pain, disability, disease and even death. According to International Labor Organization Publication (199...