IMPORTANCE OF PERIFOLLICULAR VASCULARITY IN PREDICTING OUTCOME IN INTRA UTERINE INSEMINATION CYCLES
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 9
Abstract
BACKGROUND Intrauterine insemination (IUI) is usually used in the infertility treatment to get a better pregnancy rate. The common conditions where it is used are unexplained infertility, endometriosis, polycystic ovarian syndrome & male factor infertility. Various approaches have been suggested to increase the pregnancy rate in IUI cycles, e.g. double insemination, identification of conception cycles with use of colour Doppler sonography and prevention of premature LH surge. The capillary network of preovulatory follicles have been found to be more extensive in comparison to other follicles. The use of power Doppler in assessing perifollicular blood flow can be used to determine the quality of the oocyte. This information helps to predict the success of ART cycles. Aims and Objectives- The aim of this study was to assess if we can use perifollicular vascularity in a follicle in IUI cycles to predict treatment outcome. Settings & Design- Prospective Observational study. MATERIALS AND METHODS The study included 178 consecutive IUI cycles. The perifollicular blood flow on the day of HCG was measured. According to the power Doppler signal, the patients were divided into 3 groups. Group A consisted of patients with a perifollicular blood flow of 76% to 100%. Group B with a perifollicular blood flow of 51% to 75% & Group C with a perifollicular blood flow of 0% to 50%. Clinical pregnancy rates were compared. Statistical Analysis- Statistical analysis was done using MEDCALC software. Data was statistically analysed by using by Student's ‘t’ test. Proportions were analysed using the chi-square test. Results were expressed as mean and standard error of the mean. p<0.05 was considered a statistically significant difference. RESULTS In our study, clinical pregnancy occurred in 17 patients in Group A with a clinical pregnancy rate of 21% whereas 4 cases had a clinical pregnancy in Group B with a clinical pregnancy rate of 6.6%. No clinical pregnancy was reported in Group C. There was significant statistical difference between the 3 groups as per the pregnancy rate. CONCLUSION Perifollicular vascularity assessment by transvaginal power Doppler ultrasonography plays a great role in predicting the outcome of stimulated IUI cycles.
Authors and Affiliations
Rajat Kumar Ray, Sunita Samal
Keywords
Related Articles
- EP ID EP555105
- DOI 10.14260/jemds/2019/130
- Views 98
- Downloads 0
ROLE OF COMPUTED TOMOGRAPHY IN EVALUATION OF PARENCHYMAL FOCAL LESIONS OF LIVER
[b] BACKGROUND[/b]: Of the various pathologies that afflict the liver, liver masses form an important group. Computed tomography (CT) is the imaging modality most often used to evaluate focal liver lesions. [b]...
FNAC ACCURACY IN DIAGNOSIS OF BREAST LESIONS
[b]BACKGROUND: [/b]Malignancy of breast imposes significant reduction in life span. The prognosis of breast cancer is primarily dependent on the extent of disease and also early diagnosis in important. FNAC is a wide...
STUDY ON PREVALENCE OF ARI (ACUTE RESPIRATORY INFECTION) AMONG UNDER-FIVE CHILDREN OF A RURAL AREA OF MANIPUR, THANGA: A CROSS-SECTIONAL STUDY
[b]BACKGROUND: [/b]Children are the most precious assets of a country and their health status is highly reliable index of nation’s health. [b]OBJECTIVE[/b]: To determine prevalence of ARI among under-five children in...
A CLINICAL PROFILE OF TUBERCULOSIS IN CKD PATIENTS AND THE RESPONSE TO MODIFIED ATT
BACKGROUND Tuberculosis (TB) is one of the major causes of mortality across the world. Patients with CKD are at high risk of developing TB due to the immunosuppressive effects of uraemia. There is limited information on...
DIETARY PATTERN IN THYROID DISORDERS
BACKGROUND It is known that excess iodine can cause thyroid dysfunction. Some studies show that iodine supplementation is related to increased incidence of papillary carcinoma. But this has not been clearly proved. Aims...