Importance of Simultaneous Treatment of Obesity and Diabetes Mellitus: A Sequelae to the Understanding of Diabesity-A Review
Journal Title: Obesity Research - Open Journal - Year 2019, Vol 6, Issue 1
Abstract
Aim With the growing epidemic of obesity in children, adolescents and adults globally, obesity has been found to be a risk factor for many non-communicable diseases like type 2 diabetes mellitus (T2DM), hypertension, dyslipidemias and many cancers. So much so that recently a term diabesity (Obesity and diabetes in the same patient, especially when the obesity had a causal influence on the diabetes) got introduced. The aim of this systematic review was to study how we can tackle together so that we can take care of the mortality caused by obesity and T2DM being responsible for more mortalities replacing malnutrition even in developing countries. Methods We carried out a PubMed search, along with Excerpta Medica dataBASE (EMBASE)/Cochrane library, web sciences for the Medical Subject Headings (MeSH) Terms “obesity’’, “diabetes mellitus (DM)’’, “lifestyle including exercise’’, “diet therapy for management of diabesity’’, pharmacotherapy including foods rich in antidiabetics like anthocyanins’’, “polyphenols’’, “walnuts’’, “monoterpenes’’ for same including “bariatric surgery (BS)’’. Results We found a total of 86,283 articles pertaining to obesity and DM together of which we selected 92 articles for this review after getting articles after searching cross references. No meta-analysis was done. Conclusion Till date body mass index (BMI) is used to classify overweight and obesity. With decreased muscle mass being common in these obese patients it is important to measure the body composition. Further, one has to monitor body composition when getting the patient to lose weight. Importantly, the criterion used for labelling obesity also varies in different geographical areas in view of different phenotype of diabetes in South Asia. Weight loss can be achieved using lifestyle interventions like diet, exercise and importance of combining natural products from food in attaining weight loss along with controlling hyperglycemia utilizing pharmacotherapies obesity and T2DM, control. Bariatric Surgery (BS) remains the last resort for morbidly obese although it might have to be resorted in individuals where diabetes is resistant to medical treatment and be needed for those with BMI greater than 35 kg/m2 or even less in case of resistant diabetics. Role of diets rich in walnuts, anthrocyanins, soyabean, chickpeas, curcumin, polyphenols and other vitamins and micronutrients including vitamin A, also needs to be considered while treating diabesity.
Authors and Affiliations
Kulvinder Kochar Kaur
Keywords
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- EP ID EP649520
- DOI 10.17140/OROJ-6-136
- Views 105
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