Improvement Of Inactivated Equine Herpes Virus-1 Vaccine Using Carbomer

Journal Title: Journal of Applied Veterinary Sciences - Year 2021, Vol 6, Issue 1

Abstract

An inactivated Equine herpes virus-1 vaccine was successfully improved using carbomer as adjuvant inducing high and long immunity in vaccinated mares in comparison with the convention one adjuvanted with Al-hydra gel and saponin. Such purpose was established by using 0.5% carbomer as adjuvant to the inactivated EHV-1. The applied quality control tests carried out on such vaccine revealed that it is free from foreign contaminants, safe in pregnant mares and mice and potent induced high levels of specific EHV-1 antibodies in vaccinated Guinea pigs and mares as measure by ELISA and SNT. This immunity was sufficient to protect vaccinated horses up to 28 weeks (7months) post-vaccination.

Authors and Affiliations

Safaa, A. Warda; Naglaa, I. Ali; Fatma, F. Warda; Ekbal, M. Farouk and Lubna, F. Farahat

Keywords

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  • EP ID EP692777
  • DOI https://dx.doi.org/10.21608/javs.2021.140080
  • Views 137
  • Downloads 0

How To Cite

Safaa, A. Warda; Naglaa, I. Ali; Fatma, F. Warda; Ekbal, M. Farouk and Lubna, F. Farahat (2021). Improvement Of Inactivated Equine Herpes Virus-1 Vaccine Using Carbomer. Journal of Applied Veterinary Sciences, 6(1), -. https://europub.co.uk/articles/-A-692777