IN SILICO STUDIES ON DENGUE AND SARS CORONA VIRAL PROTEINS WITH SELECTED CORIANDRUM SATIVUM LEAVES CONSTITUENTS
Journal Title: World Journal of Advance Healthcare Research - Year 2018, Vol 2, Issue 6
Abstract
Dengue virus contains seven proteins and SARS Corona virus contains twelve proteins. Recent studies have shown that these proteins are considered to be the most effective for drug designing in humans. Phytochemicals present in Coriandrum sativum leaves are found to have anti-inflamatory and antifungal properties. In our study, the binding efficiency of 4 compounds that is present in the Coriandrum sativum leaves with all these two viral proteins were performed through Insilico methods. By our virtual screening and molecular docking result, we found that squalene and n-hexadecenoic acid have highest binding affinity with these proteins.
Authors and Affiliations
Balasubramanian Sathyamurthy
Keywords
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