IN VITRO ANTIBACTERIAL ACTIVITY OF METHANOLIC EXTRACT FROM SOME HERBAL PLANTS
Journal Title: Journal of Biological and Scientific Opinion - Year 2015, Vol 3, Issue 3
Abstract
Traditionally plants have been used as medicine for treatment of dermatophytes, burns and infectious diseases is common in traditional medicine. Based on ethnopharmacological and taxonomic information, antibacterial activities of methanol extracts of some herbal plants were determined by in vitro by agar diffusion-method against some human pathogenic bacteria. In this study, methnolic extract of four plants, viz Carum copticum (Ajwain), Bacopa monnieri ( Brahmi ), Rauvolfia serpentina (Sarpagandha) and Curcuma longa ( Haldi) , which have some ethnomedicinal applications were screened for their antbacterial activity against four bacterial pathogen; two Gram’s positive Staphylococcus aureus and Bacillus amyloliquifaciens and two Gram’s negative; Escherichia coli and Pseudomanas aeruginosa. The plant extract were more active against Gram-positive bacteria than against Gram-negative bacteria. Data showed methanolic extract of T. copticum and B. monnieri showed the more antibacterial activity compared to C. longa and R. serpentina at 1mg/mL, 0.8mg/mL, 0.5mg/mL, 0.3 mg/mL. Hence these plants can be further subjected to isolation of the therapeutic antimicrobials and pharmacological evaluation. This study supports the use of herbal extract as traditional medicines to cure many diseases like intestinal tract, ear infections, throat, diarrhoea, skin diseases and fever.
Authors and Affiliations
Pavan Agrawal, Shruti Agrawal
Keywords
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- EP ID EP101163
- DOI 10.7897/2321-6328.03327
- Views 119
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