Abstract

Objective: To identify the antibacterial activity of Desmodium gangeticum (D. gangeticum). Methods: Antibacterial activity of D. gangeticum was tested with various solvents viz., methanol, ethanol, chloroform and aqueous extract against various bacterial pathogens such as Klebsiella pneumoniae, Escherichia coli, Salmonella typhi, Streptococcus mutants and Pseudomonas aeruginosa. Antibiotic sensitivity assay was performed with amoxicillin, kanamycin, tetracyclin, ciprofloxacin and penicillin. Result: Of the selected several extract, the methanolic extract showed maximum zone of inhibition (24依2.3mm) against S. mutants and minimum zone of inhibition was observed with aqueous extract against P. aeruginosa (7依0.08). In addition the antibiotic sensitivity was observed with kanamycin, tetracyclin, ciprofloxacin against all bacterias. Conclusions: The methonalic extract of D. gangeticum be able to use as potential antibacterial source for various infective pathogens.

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