IN VITRO ANTICANCER ACTIVITY OF PUNICA GRANATUM FRUIT JUICE EXTRACT AGAINST OVARIAN CANCER AND OSTEOSARCOMA CELL LINES
Journal Title: World Journal of Pharmaceutical and life sciences - Year 2018, Vol 4, Issue 5
Abstract
The plant has a long history of numerous traditional and ethno botanical application in diverse cultures. Punica granatum (Lythraceae) is traditionally used for anti-fungal, antioxidant, antimicrobial, anti-cancer and anti- bacterial activity. In the present study, In vitro anticancer activity of acetone extract of pomegranate juice was carried out in PA-1 cell line and MG 63 cell line through MTT assay method. The IC50 value of Punica granatum fruit extract was found to be 50.91 for ovarian cancer cell line (PA-1) and 52.76 for osteosarcoma cell line (MG 63). This has concluded that the pomegranate juice extract possess anticancer effect on ovarian cancer and osteosarcoma cell line due to the presence of flavonoids.
Authors and Affiliations
Sakthi Abirami M.
Keywords
Related Articles
- EP ID EP655610
- DOI -
- Views 156
- Downloads 0
DASHMOOLA FOR THE CURE OF LIFE
India is known for its traditional medicinal systems namely Ayurveda. The ayurvedic formulations are multicomponent mixtures containing plants, animals derived Products, minerals and metals and Dashmoola is considered to...
HERBAL DRUGS: A BOON FOR CANCER PATIENT
Cancer accounts for major deaths in the world. In 2016, 8.9 million people have died from various forms of cancer. Due to lack of full response in specific tissue that maintains cellular differentiation, proliferation, s...
SYNTHESIS, CHARACTERIZATION, ANTI-INFLAMMATORY AND ANTIMICROBIAL ACTIVITIES OF SOME NOVEL DIHYDROPYRIMIDINONE DERIVED PYRAZOLINES
A novel series of dihydropyramidinone derived pyrazoles were synthesized from dihydropyrimidinones by acid mediated method. The newly synthesized compounds were purified by recrystallization and characterized the compoun...
ROLE OF VAMANA KARMA AND NIMBADI CHURNA WITH PATOLADI KWATHA AS ANUPANA IN THE MANAGEMENT OF EKA KUSHTA W.S.R. PLAQUE PSORIASIS
In today‟s world everyone sees what you appear to be. Appearance is nothing but the skin. Skin diseases are affecting the mankind since time immortal. Skin is a mirror that reflects external and internal pathology, and i...
BIOEFFICACY AND PHYTOCHEMICAL ANALYSIS OF LEPIDAGATHIS KERALENSIS OF ACANTHACEAE
Naturally occurring substances are plants, animals and mineral origin. They are organic substances and obtained in both prelimary and secondary metabolic process, they also provide a source of medicinal since the earlies...