IN VITRO ANTICANCER ACTIVITY OF PUNICA GRANATUM FRUIT JUICE EXTRACT AGAINST OVARIAN CANCER AND OSTEOSARCOMA CELL LINES
Journal Title: World Journal of Pharmaceutical and life sciences - Year 2018, Vol 4, Issue 5
Abstract
The plant has a long history of numerous traditional and ethno botanical application in diverse cultures. Punica granatum (Lythraceae) is traditionally used for anti-fungal, antioxidant, antimicrobial, anti-cancer and anti- bacterial activity. In the present study, In vitro anticancer activity of acetone extract of pomegranate juice was carried out in PA-1 cell line and MG 63 cell line through MTT assay method. The IC50 value of Punica granatum fruit extract was found to be 50.91 for ovarian cancer cell line (PA-1) and 52.76 for osteosarcoma cell line (MG 63). This has concluded that the pomegranate juice extract possess anticancer effect on ovarian cancer and osteosarcoma cell line due to the presence of flavonoids.
Authors and Affiliations
Sakthi Abirami M.
Keywords
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