In vitro antifungal effect of Thymus vulgaris essence on Candida albicans isolated from patients with oral candidiasis
Journal Title: مجله دانشگاه علوم پزشکی شهرکرد - Year 2011, Vol 13, Issue 3
Abstract
Background and aims: Candida albicans is the most common etiologic agent of diseases caused by yeasts of Candida genus. The treatment of these infections is necessary because they may spread in neutropenic and immunosuppressed patients. Fungi resistance to some antifungal drugs is being increased. In addition, many of these drugs are toxic and expensive. Therefore, the study of natural plant products which can be effective against these fungi is necessary. Among the plants which have shown in vitro efficient biologic activity, is Thymus vulgaris. Thus the aim of this research was to study the inhibitory effect of Thymus vulgaris essence on of Candida albicans growth. Methods: In this research, fifty patients with oral candidiasis were studied. The obtained swab samples were cultured on Sabouraud Dextrose Agar supplemented with cycloheximide and chloramphenicol (SCC) medium, finally with performance of supplementary tests. 32 isolates were recognized as Candida albicans. Then we added Thymus vulgaris essence to SCC medium in different concentrations and the Minimum Inhibitory Concentration (MIC) of the essence was accounted for different suspension dilutions of Candida albicans. Results: The MIC of the Thymus vulgaris essence for the dilutions of 100, 10-1 and 10-2 of Candida albicans was 0.390µl/ medium and for dilutions of 10-3 and 10-4 were 0.195 and 0.0975 µl/ medium. Conclusion: The Thymus vulgaris essence has a very good antifungal effect against Candida albicans so that low amounts it can inhibit Candida albicans growth.
Authors and Affiliations
Mohammad Ziya, Mansour Bayat, Hosein Khalkhali
Keywords
Related Articles
- EP ID EP85765
- DOI -
- Views 110
- Downloads 0
Measurement of AChE activity in the brain of sea, well- and river-fed white fish (Rutilus frisi) as a health index
Background and aim: Organophosphorous (OP) compounds are widely used as pesticides, insecticides and herbicides in cultivation areas such as Mazandaran. These agents affect the environment and human health. The aim of th...
سميت كبدي عصاره آبي، متانولي و فراكسيون هاي عصاره متانولي گياه سرخاب (Phytolacca americana) به روش پرفيوژن كبدي در موش صحرائي نر
چکیده: زمينه و هدف: سرخاب با نام علمي Phytolacca americana گیاه بومي ايالت هاي مختلف آمريكا است که به صورت گسترده مصرف مي شود. برگ هاي پخته آن به سالاد مادر بزرگ (Grandmother salad) معروف است و در ايران در نوار ساحلي و...
میزان آگاهی و عملکرد عوامل خطر ابتلا به كيست هيداتيك در شهرستان لردگان استان چهارمحال و بختياري در سال 1383<br /> <br />
چکیده: زمينه و هدف: كيست هيداتيك يكي از بيماريهاي مشترك بين انسان و دام است كه از شيوع نسبتا گسترده اي در دنيا برخوردار می باشد. استان چهارمحال و بختياري به دليل وجود شغل دامپروري يكي از نقاط بالقوه پر خطر اين بيماري اس...
Comparison of actions of botulinum toxin A, between two frontal injections
Background and aim: Beautiful appearance is important for many people particularly with aging. Botulinum A toxin has been used for cosmetic purposes for several years. One of its applications is removal of hyper dynamic...
بررسی تیتر آنتی بادی ضد هاری در افراد دریافت کننده واکسن ضد هاری در شهرستان شهرکرد
زمينه و هدف: هاری بیماری ویروسی است که معمولاً بعد از گزش توسط حیوان هار روی می¬دهد. واکسیناسیون ضد هاری نقش مهمی در پروفیلاکسی بعد از برخورد با عامل بیماری دارد. این تحقیق به منظور تعیین تیتر آنتی بادی در افرادی که در ش...