IN-VITRO ANTIOXIDANT ACTIVITY AND FREE RADICAL SCAVENGING POTENTIAL OF ROOTS OF RED SAGE
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2015, Vol 8, Issue 2
Abstract
Objective: The objective of the present work is to study the in-vitro anti-oxidant activities of petroleum ether, ethyl acetate and methanolic extractsof Salvia splendens roots.Methods: The extracts were studied using 1,1-diphenyl-2-picryl hydrazyl, hydrogen peroxide (H2O2), total phenolic content (TPC) and total flavonoidcontent (TFC). The TPC and TFC were estimated taking gallic acid and rutin calibration curve respectably.Results: All the extracts possess in-vitro anti-oxidant activities. However, the order of possessing activities were methanolic > ethyl acetate > petroleumether extracts of S. splendens roots. The TPC and TFC was highest in methanolic extract.Conclusion: It can be concluded that S. splendens roots extracts possess anti-oxidant activities. The methanolic extract of S. splendens roots possesshighest anti-oxidant activity in-vitro.Keywords: Salvia splendens, In-vitro anti-oxidant, 1,1-diphenyl-2-picryl hydrazyl, Ferric reducing power activity, Hydrogen peroxide scavanging, Totalphenolic content, Total flavonoid contentÂ
Authors and Affiliations
Sailesh Narayan
Keywords
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