In Vitro Antiurolithiatic Activity of Kalyana Ksharam – A Herbo Mineral Formulation

Abstract

PURPOSE To evaluate the in vitro antiurolithiatic activity of Kalyana Ksharam (KK). MATERIALS AND METHODS Inhibition of calcium oxalate (CaOx) crystal formation by KK was investigated by four different methods, namely, nucleation, aggregation, artificial urine and dissolution method. In nucleation, aggregation and artificial urine assay, the effectiveness of KK at different concentration (100, 200, 400, 600, 800 and 1000 µg/ml) on CaOx crystallization in vitro was evaluated, while in dissolution method the percentage of dissolution of CaOx crystals was investigated. RESULTS KK was effective in inhibiting CaOx crystals in dose-dependent manner and was comparable to that of cystone. CONCLUSIONS The present study suggests that KK has potential effect on in vitro inhibition of CaOx crystals.

Authors and Affiliations

Padmapriya G, Vimalavathini R, Kavimani S

Keywords

Related Articles

Congenital Meningocele & Hydrocephalus, When to Operate in One or Two Sessions

Aim To know what cases operated upon in one session rather than two sessions for neonates with congenital meningocele associated with hydrocephalus. Background A meningomyelocele is common birth defect(0.2-2/1000 live b...

The Impact of Frailty in the Outcomes of Hip Fracture Surgery in the Elderly Patients

Osteoporotic hip fracture is as common health issue in an elderly population. With ageing, frailty comes into play as a complex geriatric syndrome. Studies have shown that frailty has negative consequences in the outcome...

Mobile Asthma Action Plan for Adolescent with Asthma

Asthma is the most common health problems in adolescents. Self-management is one way to improve health status in an adolescent with asthma. Mobile technology has the potential to improve self-management in adolescents wi...

Effect of Free Radical/Antioxidants in Human Body

The presence of one unpaired electron in a molecule is called free radical. When oxygen interacts with certain molecules in chemical reaction it produces atoms or group of atoms with unpaired electrons called free radica...

A COMPARATIVE STUDY ON GENATIC INFLUENCE ON TEMPERAMENT OF MONOZYGOTIC TWINS IN TWO CULTURAL ZONES

The study was to compare the temperament of monozygotic twins in the age group of 4 -10 years. The present study was conducted in four districts namely; Hisar Fatehabad, Rohtak, and Jind of Haryana state with the purpose...

Download PDF file
  • EP ID EP672915
  • DOI 10.24247/ijmpsoct20192
  • Views 116
  • Downloads 0

How To Cite

Padmapriya G, Vimalavathini R, Kavimani S (2019). In Vitro Antiurolithiatic Activity of Kalyana Ksharam – A Herbo Mineral Formulation. International Journal of Medicine and Pharmaceutical Sciences (IJMPS), 9(5), 7-14. https://europub.co.uk/articles/-A-672915