In-vitro evaluation of Scoparia dulcis Linn. for anti – urolithiatic activity
Journal Title: The Journal of Phytopharmacology - Year 2018, Vol 7, Issue 3
Abstract
Introduction: Urolithiasis is a complex process that occurs from series of several physicochemical event including super-saturation, nucleation, growth, aggregation and retention within the kidneys. Data from invitro, in- vivo and clinical trials reveal that phytotherapeutic agents could be useful as either alternative or an adjunct therapy in the management of Urolithiasis. Scoparia dulcis (L.) have been reported to possess antiurolithiatic property by various folk lore practitioners. Methods: The in- vitro antiurolithiatic study of the whole plant of S. dulcis (L). through titrimetric and turbidity method to check their potential in dissolving calcium oxalate crystals using Cystone as the standard compound Result: The aqueous extract showed relatively higher dissolution of 66.96% of stones than the alcoholic extract. The turbidity showed by the alcohol extract and the aqueous extract of test drug (S. dulcis (L).) was highly significant compared to the standard (Cystone).
Authors and Affiliations
Hima Sasidharan, Suma Venkatesh Mallya, Prabhu Suchitra, Koppala Narayana Sunil Kumar
Keywords
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