IN VITRO STUDY ON ANTIOXIDANT ACTIVITY OF METHANOLIC LEAF EXTRACT OF PIPER BETLE LINN
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 24
Abstract
BACKGROUND The use of medicinal plants for maintaining good health is getting attention worldwide. Antioxidants play an important role in preventing damage caused by oxidative stress. In the present study, methanolic leaf extract of Piper betle Linn plant of central Kerala was evaluated for antioxidant activity. Phytochemical investigation confirmed the presence of bioactive ingredients in the extract. MATERIALS AND METHODS The antioxidant activity of methanolic extract of Piper betle Linn leaf was evaluated using DPPH free radical assay. DPPH (1, 1- diphenyl-2-picrylhydrazyl) free radical analysis is one of the accurate and frequently employed methods for evaluating antioxidant activity. RESULTS The methanolic leaf extract of Piper betle Linn demonstrated antioxidant activity. As concentration increases, radical scavenging activity increases. CONCLUSION Scientific evidence suggests that antioxidants reduce the risk for chronic diseases including cancer and heart disease and infectious diseases. Further evaluation of pharmacological activities of Piper betle may prove useful in treatment of cancer and heart diseases
Authors and Affiliations
Bindhu R. Kamath, Sabeena K
Keywords
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- DOI 10.14260/jemds/2018/646
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