In vivo analgesic and anti-inflammatory properties of the aqueous extract of Pistacia atlantica Desf. from Morocco
Journal Title: Journal of Ayurvedic and Herbal Medicine - Year 2017, Vol 3, Issue 4
Abstract
The present study analyses the pharmacological activity in vivo models of the aqueous extract obtained from Pistacia atlantica Desf of Morocco. The plant selected for this study have been used in traditional medicine in Morocco for the treatment of various diseases that are considered as inflammation in nature, e.g. arthritis, rheumatism, fever, and related inflammatory diseases. The result of this study showed that the aqueous extract of Pistacia atlantica Desf. lacked toxicity, but exhibited a high analgesic effect in writhing Test and in tail immersion Test suggesting the induction of a peripheral and central analgesic response. The aqueousextract of this plant also exhibited an anti-inflammatory action inhibiting the rat paw edema induced by carrageenin and experimental trauma. We can conclude that the aqueousextractof Pistacia atlantica Desf. Possesses potential anti-inflammatory activities, supporting the traditional application of this plant in treating various diseases associated with inflammation and pain in Morocco.
Authors and Affiliations
Ghizlane Hajjaj, Aziz Bahlouli, Mouna Tajani, Yahia Cherrah, Amina Zellou
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