Incidence and Severity of Oral Mucositis in Patients of Head and Neck Cancers Receiving Definitive Radiotherapy with or without Chemotherapy: A Hospital Based Study
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 2
Abstract
Background: Head and neck cancers are among the ten most frequent cancers in the world and constitute 5% of all cancers worldwide. In developing countries like ours, cancer of the head and neck is among one of the commonest cancers. They account for one fourth of male and one-tenth of female cancers in India. Radiotherapy, with or without chemotherapy, is the mainstay of the treatment and oral mucositis is one of the major complaint and side-effect of the treatment in head and neck cancer patients. Material and Method: The present study comprised of total of 150 head & neck cancer patients receiving treatment at MD Oswal Cancer Hospital were enrolled in this study. Any Head and Neck Squamous cell carcinoma (AJCC Stage I-IV, M0 vide appendix no. I) patient receiving Radiation dose more than or equal to 56 gray, weekly concomitant chemoradiation in the form of Cis-platinum, Gemcitabine or Paclitaxel alternating with Gemcitabine were enrolled in this study. Results: Oral mucositis incidence was noted in 100% of the patients with chemo-radiation & was irrespective of chemotherapy used. The frequency of severe oral mucositis was 50% in radiotherapy alone group while 54.03% in chemoradiation group. Incidence of mucositis grade IV was more with cis-platinum being used as radio-sensitizer (62.9%) and was seen least in the gemcitabine arm (41.4%). Mean treatment time in all patients was almost same and around 59 days and it was not affected by the chemotherapy used. Conclusion: Severe oral mucositis (grade III and IV) was observed more in smokers, alcoholics, diabetics, opium addicts and patients having bad ODH. Mucositis resolves within 4-5 weeks period after the completion of treatment.
Authors and Affiliations
Pardeep Garg, Parveen Kaur, Rajesh Vashistha, Rupinder Singh, Ishu Sharma
Keywords
Related Articles
- EP ID EP544135
- DOI 10.21276/ijmrp.2017.3.2.043
- Views 70
- Downloads 0
Attitude Assessment Regarding HIV/AIDS among Attendees of Integrated Counselling and Testing Centre at SMS Medical College, Jaipur
Introduction: Social taboos related to sex issues contribute for the spread of HIV/AIDS.This study was carried out at ICTC at SMS Medical College, Jaipur 1) to determine the attitude of ICTC attendees and 2) to correlate...
Prevalence and Risk Factors Associated with Nocturnal Enuresis Among Primary School Children in Al-Eskan Region, Makkah Al-Mokarramah
Background: Nocturnal enuresis is a common problem worldwide among children and adolescents, across all races and cultures, but usually underreported. Though this condition is labeled benign, it often leads to important...
Assessment of the Complications Associated With Tooth-Supported Fixed Dental Prosthesis at Qassim Region, Saudi Arabia
Purpose: This study was conducted to identify and assess the complications associated with tooth-supported fixed dental prosthesis among dental patients in Qassim Region, Saudi Arabia, and the most common problems the pa...
Histological Analysis of Primary Brain Tumors in a Tertiary Care Hospital: A Retrospective Study of 5 Years
Background: Central nervous system neoplasms represent a unique heterogeneous population of neoplasms and include both benign and malignant tumors. The objective of this article is to provide an overview of the descripti...
The Prevalence of Mandibular Third Molar Angulation in Patients Who Attended Arar Specialist Dental Centre: Panoramic Survey
Aims: This study was carried out to investigate about the prevalence of mandibular third molar angulations and which specific type of angulation is more prevalent and the classification of impaction if present according...