Incidence of Carcinoma Prostate in Cases of Benign Prostatic Hyperplasia in Rims Ranchi Jharkhand
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Benign prostatic hyperplasia (BPH) is characterised by the non-malignant overgrowth of prostatic tissue surrounding the urethra, ultimately constricting the urethral opening, and giving rise to associate lower urinary tract symptoms. This was a prospective observational study of the histopathological findings of biopsy of patients undergoing TURP or open prostatectomy for obstructive urinary symptoms due to BPH admitted to Rajendra Institute of Medical Sciences, from January 2017 to October 2018. Those cases, with elevated age adjusted PSA values, abnormal DRE, documented UTI and proved adenocarcinoma prostate (CaP) were excluded from the study. 100 patients included in the study. Out of 100 BPH cases 8 cases were found to have occult carcinoma prostate on histopathological examination with overall incidence of 8%. Highest incidence was observed in the age group >80 years, which was 33.3%. Lowest incidence was seen in the age group 51-60 years, which was 2.2%, whereas it was nil in age groups below 50 years. The average age of incidence of occult carcinoma prostate was 60 years. A definite increase in the incidence of occult carcinoma prostate in BPH cases was observed with advancing age. Out of 8 cases of occult carcinoma detected, 7 cases were nonvegetarian and one was vegetarian, reflecting a higher incidence among the former. A positive family history was found in 3 out of 8 cases. Incidence of occult prostate cancer was only observed in open prostatectomy specimen.
Authors and Affiliations
Dr. Jyoti Kumari, Dr. Samir Toppo, Dr. Vinay Pratap
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