Incidence of Helicobacter Pylori in upper gastrointestinal lesion
Journal Title: International Journal of Medical Research and Review - Year 2018, Vol 6, Issue 1
Abstract
Introduction: Helicobacter pylori are gram-negative bacillus. It is noninvasive and live in gastric mucus, with the small proportion of bacteria adherent to the mucosa. Its spiral shape and flagella render Helicobacter pylori motile in mucus environment. Helicobacter pylori is an important pathogen in human causing chronic gastritis and playing a major role in the development of peptic ulcers and gastric cancer. Material and Methods: Study was conducted in Mahatma Gandhi Medical College and hospital, Jaipur (from Jan 2014 to March 2015). 57 Gastrointestinal biopsies were taken who have symptom of dyspepsia. All biopsies taken from different sites were brought in 10% buffered formalin. After overnight fixation in formalin, the tissues were processed in automated tissue processor for dehydration, clearing, and paraffin embedding. Section were cut in rotary microtome at 4 micrometer thickness. The section was stained for Hematoxylin and Eosin stain and Geimsa overnight stain. Result: The present studyincluded 57 cases of upper GIT biopsies (gastro esophageal duodenal biopsies). The incidence of Helicobacter Pylori was seen with chronic gastritis in our study. Conclusion: H. pyloriare etiologically associated with chronic activegastritis, duodenal ulcer, gastric ulcer, primary gastric B-cell lymphoma or mucosal associated-lymphoid type lymphoma (MALT lymphoma) and gastric adenocarcinoma. Helicobacter pyloriinducedchronic gastritis were encountered in 16(47.22%) casesofthe presentstudy. Overnight Giemsa stain was done on all the patients and a histopathological diagnosis was made along with the study of the incidence of Helicobacterpylori positivity in all these patients.
Authors and Affiliations
Vikas Kumar, B. P. Nag, Pallavi Anand, Narayani Joshi, Renu Jain
Keywords
Related Articles
- EP ID EP344698
- DOI 10.17511/ijmrr. 2018.i01.07.
- Views 137
- Downloads 0
Coarctation of aorta presenting as hypertensive encephalopathy in a young female
Coarctation of Aorta (CoA) is a congenital cardiac defect which can present in adults. The usual presentation is hypertension. Though it has subtle clinical signs but they can go undetected if not sought for. One of the...
hsTropI: an early biomarker of acute coronary syndrome & MI
In the Emergency Department cardiac troponins are the preferred biomarkers for the diagnosis of acute myocardial infarction (MI) and are useful for risk stratification of patients with acute coronary syndrome (ACS) and s...
Biological and synthetic scaffold: an extra cellular matrix for constructive tissue engineering
Worldwide many people suffering from tissue dysfunctions or damages need rapid transplantation. Tissue engineering has attracted attention as therapeutic modality aiming at repairing lost or damaged tissues. Critical ste...
A prospective, randomized, double blind controlled trial of the use of preoperative antibiotics in routine abdominal surgery: A comparative analysis between Ofloxacin + Metronidazole, Cefotaxime + Sulbactum and Cefepime +Tazobactum (Single does vs. Three doses) and their effects.
Introduction: Anti microbial prophylaxis before any elective surgery is a preferred deterrent to post operative surgical site infection now. We have used different antibiotics, two being from the cephalosporin class, one...
A cadaveric study on accessory lobes of lungs and their bronchial branching pattern
Background: An accessory lobe is a part of lung tissue separated off by an accessory fissure. It develops due to occasional monopodial branching of the stem bronchi. Different accessory lobes may be encountered in the hu...