Incidence of hypercalcemia among patients<br /> with tuberculosis before antituberculosis chemotherapy
Journal Title: Αρχεία Ελληνικής Ιατρικής - Year 2003, Vol 20, Issue 5
Abstract
OBJECTIVE Hypercalcemia is known to occur in association with granulomatous diseases. The aim of this study was to ascertain the incidence of hypercalcemia and to determine the prevalence of associated symptoms in Greek patients with newly diagnosed tuberculosis (TB), before the initiation of antituberculosis treatment. METHOD All patients with newly diagnosed TB presenting during a 3-year period evaluated prospectively. In total, 88 patients with TB (50 males and 38 females), aged 23–89 years (mean age±SD 46.4±19 years) were evaluated and 65 age and sex-matched controls with chronic obstructive pulmonary disease (36 males and 29 females), aged 28–88 years (mean age±SD 47.2±18 years). Among the TB patients, 56 had pulmonary TB, 20 had pleural TB without evidence of pulmonary parenchymal involvement, 8 had pulmonary and pleural TB and 4 had disseminated disease. RESULTS The mean albumin-adjusted serum calcium concentration and the mean ionized calcium concentration were significantly higher in the TB group (2.49±0.21 mmoL/L and 1.27±0.02 mmoL/L, respectively) than in the control group (2.36±0.11 mmoL/L and 1.19±0.02 mmoL/L, respectively; Ρ
Authors and Affiliations
A. ROUSSOS, C. KOSTIKAS, J. LAGOGIANNI, D. KAZI, N. FILIPPOU
Keywords
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