Incidence of Metallo-β-Lactamase Producing Pseudomonas Aeruginosa Isolates and Their Antimicrobial Susceptibility Pattern in Clinical Samples from a Tertiary Care Hospital
Journal Title: International Journal of Research and Review - Year 2017, Vol 4, Issue 1
Abstract
Background and objectives: Pseudomonas aeruginosa, most common pathogen causing nosocomial infections, acquire drug resistance to more than one antimicrobial class along with production of metallo-β lactamases (MBL) is one of the most worrisome resistance mechanism. The aim of our study is to find the incidence of MBL in Pseudomonas aeruginosa isolates and their antimicrobial susceptibility pattern. Material and Methods: The study included 127 non-repetitive clinical isolates of Pseudomonas aeruginosa from various samples isolated from October 2010 to October 2011, in department of Microbiology, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan. The following tests were used - Imipenem and EDTA combined disc test, Double disc synergy test (DDST) using Imipenem and EDTA and MBL E-test along with antibiotic susceptibility testing. Result: The incidence of MBL P. aeruginosa was 15/127 (11.81%) in our study. The incidence of MBL pseudomonas was maximum in ICU patients (30%), followed by IPD patients (9.6%). None of the OPD sample grew MBL in Pseudomonas. Conclusion: Combined disc / DDST using ceftazidime have other ceftazidime resistance mechanisms; will not show MBL production and therefore, imipenem disc should be used for screening of MBL.
Authors and Affiliations
Dr. Sunita Agarwal
Keywords
Related Articles
- EP ID EP366807
- DOI -
- Views 107
- Downloads 0
To Assess Effect of Nidan Parivarjan in the Management of Padadari Vyadhi with Application Sarjaras Malahar
There is a lot of difference between today’s life style and ancient life style, hence the applications of ayurvedic principles must be modified and according to new diseases new principles should be searched. For that pu...
A Review Paper of Survey on Recent Trend of Accounting and Accounting Professional
Accountancy and accounting professional plays a vital role in modern business. It is very essential to maintain books of account for each and every business to know its profitability and its efficiency for survival of bu...
Incidence of Metallo-β-Lactamase Producing Pseudomonas Aeruginosa Isolates and Their Antimicrobial Susceptibility Pattern in Clinical Samples from a Tertiary Care Hospital
Background and objectives: Pseudomonas aeruginosa, most common pathogen causing nosocomial infections, acquire drug resistance to more than one antimicrobial class along with production of metallo-β lactamases (MBL) is o...
Acehnese Deixis Realization: A Study of Syntagmatic System
The paper is qualitative descriptive and aims to describe the Acehnese deixis realization using syntagmatic system. The results showed that the syntagmatic system in Acehnese were oriented to ideational metafunction cove...
Plant Growth Promotion Using Panchagavya
In the traditional agro practice, people have used organic nutrients panchagavya to promote plant growth. In the present, panchagavya was prepared using a modified methodology incorporating tulsi and neem oil along with...