Incidence of Rubella Antibodies among Pregnant Women in a Tertiary Care Hospital
Journal Title: Journal of Pharmaceutical and Biomedical Sciences - Year 2014, Vol 6, Issue 2
Abstract
Background In itself, the disease is trivial but rubella in pregnant women may lead to congenital malformations in the baby. Aims and Objective This study was aimed to determine and analyse the prevalence of rubella antibodies among pregnant women. Materials and Methods A total of 100 pregnant women were included in this study. Out of 100 pregnant women, 38 cases were from 1st trimester, 35 from 2nd trimester and 27 cases from 3rd trimester. About 2–3 ml of blood sample was collected aseptically from pregnant women at the antenatal clinic and was processed accordingly for detection of IgG and IgM antibodies specific for rubella virus by enzyme-linked immunosorbent assay (ELISA). Results Out of 100, 94% and 7% of pregnant women were seropositive for anti-rubella IgG and IgM antibodies, respectively. Highest seropositivity for rubella IgG was found in age group 20–25 years (97.61%) followed by 26–30 years (91.89%). Higher seropositivity for rubella IgG antibodies was observed in female residents of rural areas (94.59%) as compared to those residents of urban areas (93.65%). Conclusion Prevention of morbidity and mortality from rubella infection depends on prevention of infection in childbearing women and early recognition of maternal infection.
Authors and Affiliations
Rajesh Bareja
Keywords
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