Increased Bone Marrow 18F-Choline Uptake in a Patient with Hepatocellular Carcinoma and Thalassemia Intermedia
Journal Title: Molecular Imaging and Radionuclide Therapy - Year 2020, Vol 29, Issue 1
Abstract
A 57-year-old male with history of thalassemia intermedia and hepatocellular carcinoma underwent a positron emission tomography/computed tomography (PET/CT) scan with 18F-choline before radioembolization procedure with 90Y-microspheres. The PET/CT scan with 18F-choline demonstrated highly increased tracer incorporation within a gross lesion in the hepatic dome coupled with diffuse activity in bone marrow, this latter aspect was probably due to the compensatory hematopoiesis stimulation induced by chronic hemolysis. This pattern of skeletal 18F-choline uptake should be considered as a peculiar PET/CT finding in thalassemic patients.
Authors and Affiliations
Luca Filippi
Keywords
Related Articles
- EP ID EP684466
- DOI 10.4274/mirt.galenos.2019.03064
- Views 172
- Downloads 0
Comparison of Radiochemical and Chemical Impurities in Liquid Wastes of Two Different 68Ge/68Ga Generators used in Nuclear Medicine PET Chemistry
Objectives: Germanium-68/gallium-68 (68Ge/68Ga) generator eluate contains a number of metal cations that can compete with 68GaCl3, reducing specific radioactivity. The first step in peptide labeling with 68GaCl3 is to re...
Minimal Invasive Radioguided Ectopic Parathyroidectomy in Upper Mediastinum
In this study we wanted to present a case with the history of multiple previous neck explorations and persisting upper mediastinal ectopic parathyroid adenoma who underwent a successful operation with radioguided minimal...
Unforeseen COVID-19 on Oncologic Bone Scan with SPECT/CT in a High Prevalence Area
A 65-year-old woman with known diabetes and hypertension underwent a technetium methylene diphosphonate (Tc-99m MDP) bone scan with single photon emission computed tomography/computed tomography (SPECT/CT) for shoulder p...
Amyloidosis Associated Kidney Failure with Gross Hypermetabolic Intra-abdominal Mass
A 23-year-old male patient who presented with impaired kidney function tests attended to hospital for hemodialysis and underwent 18F-FDG positron emission tomography/computed tomography (PET/CT) examination for the metab...
The Predictive Value of Proportional Evaluation Based on the Metabolic Activity of Cervical Lymph Nodes on PET/CT Imaging in Patients with Larynx Cancer
Objectives: We aimed to evaluate the proportional values of maximum standardized uptake value (SUVmax) for cervical lymph nodes on 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) fo...