Increased Levels of Serum Cystatin C with Body Mass Index
Journal Title: Journal of Pharmaceutical and Biomedical Sciences - Year 2017, Vol 7, Issue 8
Abstract
Obesity is a major causative factor for many metabolic disorders and premature deaths in developing countries. The risk of many diseases like diabetes mellitus, cardiovascular disease, hypertension, hyperlipidemia, and cancers increases many folds in association with obesity. Cystatin C, though considered a renal marker, is associated with obesity irrespective of gender. Cystatin C mRNA is expressed in subcutaneous and omental adipose tissue, at twice higher levels in non-adipose than in adipose cells. The present study was conducted in the Department of Biochemistry, M.M. Institute of Medical Sciences and Research, Mullana, Ambala in which the levels of serum cystatin C were estimated in 100 healthy individuals in the age range of 17 years and above of either sex. All the 100 subjects included in the study were divided further into the suitable groups according to their body mass index and age. It was observed that serum cystatin C levels increase with the increase in BMI in both the age groups. These observations suggest a role for adipose tissue as a contributor to circulating concentration of cystatin C.
Authors and Affiliations
Pallavi Mahajan, Sodhi KS
Keywords
Related Articles
- EP ID EP313426
- DOI -
- Views 78
- Downloads 0
Post-Traumatic Stress Disorder A Case Study
Post traumatic stress disorder is a set of reaction to an extreme stressor such as intense fear, helplessness or horror that leads the individual to relieve the trauma. The disorder may occur at any age1. Symptoms may be...
Comparison of Safety, Efficacy and Duration of Analgesia of Intrathecal Ropivacaine Alone Versus Ropivacaine with Midazolam for Lower Abdominal and Lower Extremity Surgeries
Background Spinal anaesthesia is a common anaesthetic technique for lower abdominal and lower extremity surgeries. Many adjuvants have been tried to prolong the duration of analgesia provided by the local anaesthetics wh...
Detarium microcarpum Stem Bark Extracts Induce Apoptosis in Human Breast Adenocarcinoma MDA MB 231 Cells via cJNK Activation and Mitochondrial Cytochrome C Release
Detarium microcarpum stem bark extract (DMSE) is one of the medicinal herbs used by the traditional medical practitioners in North East Nigeria to treat or manage various ailments such as wounds, inflammation and some fo...
Is the Posed Smile Contingent on Sexual Dimorphism? – A Cross Sectional Study
Introduction Smile evaluation has become an integral part of the clinical examination. The objectives of this study were to evaluate posed smile in males and females for Morley’s ratio, buccal corridors, smile arc and di...
Assessment of Difficulty During Orotracheal Intubation In Patients With Cervical Spine Immobilization—A Comparison of Macintosh and Truview Laryngoscopes
Patients with cervical spine disease/trauma with intact or partially intact neurological status requiring endotracheal intubation present as special cases of difficult airway. Securing the airway in such patients can be...