Indicators of cytokines in children with hepatobiliary pathology combined with parasitosis
Journal Title: Гастроентерологія - Year 2018, Vol 52, Issue 1
Abstract
Background. Hepatobiliary pathology (HBP) in children tend to continual growth, and the pathology itself is characterized by a group of features that are absent in adults. The purpose was to identify the features of the blood serum cytokines in children with HBP and parasitosis. Materials and methods. The main clinical group consisted of 64 children aged 8–18 years with HBP. Comparison group included 25 healthy children matched by age and gender with the main clinical group. Results. Hepatobiliary disorders were prevalent among primary school-aged children. 64.8 % of patients with HBP were diagnosed with helminthiasis or giardiasis. The level of interleukin 4 (IL-4) in children with HBP was almost 11 times higher than that of in the comparison group, tumor necrosis factor α (TNF-α) — 6 times. The highest concentration of IL-4 and TNF-α has been reported in patients with toxocarosis and ascariasis. Conclusions. In the structure of HBP in children, functional disorders of the biliary tract were prevalent. In HBP and concomitant parasitosis (especially ascariasis and toxocarosis), IL-4 and TNF-α levels are significantly higher in patients without concomitant parasitosis.
Authors and Affiliations
T. V. Sorokman, N. A. Popelyuk, L. V. Shvygar
Keywords
Related Articles
- EP ID EP290798
- DOI 10.22141/2308-2097.52.1.2018.130776
- Views 61
- Downloads 0
Clinical and laboratory features of pancreatic steatosis in children with overweight and obesity
Background. Nonalcoholic fatty pancreas disease is a pathological condition associated with obesity and components of the metabolic syndrome. Clinical features of the pancreatic steatosis can be caused by exocrine insuff...
Enthusiast in Zemstvo Medicine in Yekaterinoslavschina — DnipropetrovschinaRegion
The article presents life journey and professional activity of Petro Sochinskiy — a zemstvo doctor, public activist, collector, folklorist, patron, full member of Yekaterinoslav Scientific Archival Committee, who made a...
Digestive Diseases and Pathology of the Spine
The aim of the work was to improve the efficiency of treatment of persons with gastroenterological diseases combined with radicular syndrome. The paper presents data on the state of the spine in patients treated at the g...
The role of biologically active substances in gastroesophageal reflux disease in patients with type 2 diabetes mellitus
Background. The factors influencing the progression and clinical manifestations of gastroesophageal reflux disease (GERD) in patients with type 2 diabetes mellitus (DM) have not been sufficiently studied so far. To inve...
Proceeding of the panel discussion “Key issues in the diagnosis and treatment of chronic inflammatory bowel diseases” at the research-to-practice conference “VII scientific session of the State Institution “Institute of Gastroenterology of the National Academy of Medical Sciences of Ukraine”. The latest technologies in theoretical and clinical gastroenterology”
No abstract