Inflammasome- A Novel Mechanism of Innate Immunity In Periodontal Disease
Journal Title: Indian Journal of Dental Advancements - Year 2016, Vol 8, Issue 2
Abstract
Periodontitis is a chronic inflammatory disease. Besides microbiota, various other risk factors also play a role in the progression of periodontal disease. Host immune system prevents the progression of periodontal disease by clearing the microbiota. Immune system consists of innate and adaptive mechanism which control of periodontal disease. Innate immune system is non-specific and various mechanisms and cells play key role in the arrest of periodontal disease. Recently the role of inflammasome complex is explored in arresting periodontal disease. This review highlights the inflammasome, the regulation and the role of inflammasome in the periodontal disease.
Authors and Affiliations
Deepthi K, Jagadish Reddy G, Raja Babu P, Vikram Reddy G
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