Inflammatory markers in essential hypertension
Journal Title: International Journal of Advanced Biochemistry Research - Year 2017, Vol 1, Issue 1
Abstract
Hypertension (HTN) is now a major health problem in India. Both environmental and genetic factors may contribute to regional and racial variations of blood pressure (B.P.) and hypertension prevalence. Obesity and weight gain are strong independent risk factor for HTN. It has been shown that, 60% of hypertensive are >20% overweight. Among population HTN prevalence is related to dietary NaCl intake and the age related increase of BP may be added by a high NaCl intake. HTN is multi-factorial disorder, any individual factor may make a comparatively small contribution to overall B.P. The most important factors in the development of HTN at the population level are calorie excess (as manifest by obesity) high salt intake, low potassium and calcium intake, physical inactivity, heavy alcohol consumption and psychosocial stress. An increased in body weight from childhood to young adulthood is a major predictor of adult HTN. HTN doubles the risk of cardiovascular diseases(CVD), including coronary heart disease (CHD), congestive heart failure (CHF), ischemic and hemorrhagic stroke, renal failure and peripheral arterial disease. High blood pressure causes chronic inflammation, chronic low grade inflammation has been an integral part in the pathogenesis of vascular disease. So, inflammation may be implicated in the development of HTN.
Authors and Affiliations
Manzura R. Mulani
Keywords
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