Inflammatory PAP smears and its microbiological association: A prospective study
Journal Title: Pathology Update: Tropical Journal of Pathology and Microbiology - Year 2017, Vol 3, Issue 3
Abstract
The infections of the genital tract are common in reproductive-age women. The Papanicolaou (Pap) test is a simple, quick, and painless cytology procedure, based on picking up of cells from the uterine cervix and used as a screening test for the prevention of the cancer of uterine cervix and the possible presence of infection based on cytological criteria [1]. The diagnosis of infections in cervical smear tests is based on cytological criteria. Non-specific cervicitis or inflammatory changes in a smear report are most common. The management protocol of such patients is unclear and need further testing by conventional and ancillary microbiological investigations or inflammatory change should be considered as minor. The most common complaint in the reproductive age group is vaginal discharge. Symptomatic vaginal discharge is caused by inflammation due to infection of the vaginal mucosa. It occurs in 1-14% of all women in the reproductive age group and the prevalence of vaginal discharge in India is estimated to be 30% [2]. The complications of untreated vaginal infections can lead to vaginitis, pelvic inflammatory diseases, infertility, endometriosis, urethral syndrome, pregnancy loss, preterm labour. Among the cases of vaginal discharge, Bacterial vaginosis is commonest cause followed by Candidiasis and Trichomoniasis. The addition of a simple microscopic evaluation by Gram stain of the vaginal smear and wet mount visualization of motile Trichomonas vaginalis has evolved as a sensitive noncultural diagnostic technique for Bacterial vaginosis, Candidiasis and Trichomoniasis, respectively. This study aimed to investigate the prevalence of pathogenic vaginal microorganisms and the presence of inflammation in Pap smear and to evaluate the possible co-infection of these organisms and association of dysplasia/ malignancy in them.
Authors and Affiliations
Shashikant Adlekha, Tandra Chadha
Keywords
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- EP ID EP264203
- DOI 10.17511/jopm.2017.i3.05
- Views 123
- Downloads 0
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