INFLUENCE OF MILD IODINE DEFICIENCY AND LATENT IRON DEFICIENCY ON THE TYPE OF REACTION OF CARDIOVASCULAR SYSTEM IN PHYSICAL ACTIVITY
Journal Title: Український журнал медицини, біології та спорту - Year 2017, Vol 4, Issue 2
Abstract
The study involved 133 practically healthy (group of health I and II) children (68 boys and 65 girls), who were divided according to the age into two groups: Ist (n=68) – children aged from 6 to 11 years, IInd (n=65) – children from 12 to 18 years. In each age group all the children were divided into four subgroups: 1st – boys and girls with appropriate iodine and iron supply (control group), 2nd – children with limited iodine supply without iron deficiency, 3rd – with proper iodine supply and latent iron deficiency, 4th – with mild iodine deficiency and latent iron deficiency. In order to study thyroid gland function in blood serum samples, the contents of thyroid hormones were determined: free T3 (fT3) and T4 (fT4), thyroid stimulating hormone adenohypophysis (TSH). To determine the rate of iodine supply the index of urinary iodine excretion in urine single portions according to Sandell-Kolthoff reaction the median urinary iodine (Me) was found. Results of morphometry of the thyroid gland were evaluated according to the standards of thyroid volume (97 percentile) considering the sex and body surface area. To evaluate iron metabolism in children the level of hemoglobin (Hb) in capillary blood, serum iron (SI) level, commonbinding capacity of serum (CBCS) with the help of ELISA test (test kit «Cormay», Poland) were measured. Condition of iron stores was characterized by the level of serum ferritin (SF) level. Type of the reactions of cardiovascular system to the dosed physical activity was assessed using sample of Martine-Kushelevsky and counting the quality reaction index (QRI). To analyze the parameters of thyroid status in pupils with mild iodine deficiency (2nd and 4th subgroups), the reduction of fT3contents (at 18.5–19.9%, p<0.05) and fT4 (at 14.9- 20.8%, p<0.05) regardless of age and gender is determined. Also in these subgroups the increase of TSH in blood serum of boys at 2.5–2.6 times (p<0.05), in girls – at 2.8–3.4 times (p<0.05) is observed. These changes were associated with a decrease of the SI (at 44.9 –53.6%, p<0.05), ferritin (at 43.5–69.0%, p<0.05) and were accompanied by the growth of CBCS (at 70.9–73.6%, p<0.05) as for the control. Iodine the reaction by QRI was the next one: it was good in 25% of boys and 22.2% of girls; satisfactory – in 50% of boys and 66.7% of girls; irrational – in 25% of boys and 11.1% of girls. Reaction to physical exercise in all children of this group is according to normotonic type; the recovery period does not exceed 3 minutes. In pupils with latent iron deficiency reaction by QRI was good in 37.5% of children and satisfactory in 62.5% of patients, the response to physical activity in all children is normotonic and recovery period does not exceed 3 minutes. On the basis of the combined trace element imbalance the reaction is good, normotonic in 11.1% of boys and 25% of girls; satisfactory in 55.6% of boys and 50% of girls; irrational – in 33.3% of boys and 25% of girls, including 66.7% of boys and 50% of girls whose reaction is by hypotonic type, and the recovery period was an average 5.3 minutes. The same tendency is in the IInd age group (pupils aged 12–18). At the same time in the 4th subgroup only 25% of children have good, normotonic reaction; 50% of boys and 37.5% of girls – satisfactory, normotonic reaction; 25% of boys and 37.5% of girls – poor reaction, of them in 12.5% of girls – it was hypertonic type of reaction with the recovery period of 4.5 minutes. On the basis of the trace element imbalance the thyroid homeostasis is impaired in pupils; it is accompanied by exhaustion of reserve-adaptive capacities.
Authors and Affiliations
U. Shalamay, N. Voronych-Semchenko
Keywords
Related Articles
- EP ID EP265089
- DOI -
- Views 136
- Downloads 0
НЕСПЕЦИФІЧНА РЕЗИСТЕНТНІСТЬ ОРГАНІЗМУ В УМОВАХ НАБУТОЇ КОРОТКОЗОРОСТІ СЛАБКОГО ТА ВИСОКОГО СТУПЕНЮ
У статті представлені результати клінікоімунологічного дослідження стану неспецифічної резистентності організму людини в умовах патологічного стану набутої короткозорості. Недостатність фагоцитарної активності нейтрофілі...
ЕФЕКТИВНІСТЬ ЗАСТОСУВАННЯ КОМБІНАЦІЇ ІНФУЛГАНА З РЕВМОКСИКАМОМ ДЛЯ ПІСЛЯОПЕРАЦІЙНОГО ЗНЕБОЛЮВАННЯ ГЕРОНТОЛОГІЧНИХ ХВОРИХ З ПОЛІТРАВМОЮ
Мета роботи – визначення ефективності застосування комбінації інфулгана з ревмоксикамом для післяопераційного знеболювання геронтологічних хворих з політравмою. Було обстежено 32 пацієнта у віці старше 60 років з наявні...
Peculiarities of Structural Organization of Myocardium in Old Rats with Simulated Alimentary Obesity at the Background of Cryopreserved Cord Blood Nucleated Cell Administration
Alimentary obesity is a chronic disease with a multifactorial nature, being largely stipulated by a lack of motor activity and hypercaloric nutrition. The obesity increases the morbidity and mortality risks because of va...
Morphogenetic Peculiarities of Plumbum Acetate Isolated and Combined with Argentum Citrate Effects Formation and its Influence on Rat’s Placenta Development
Potentially harmful effects of certain chemical factors determination, in particular heavy metal salts, have become especially relevant today as a result of the infertility rate and pathologies of the motherplacenta- fet...
УСТРАНЕНИЕ СТУПЕНЧАТОГО УСТУПА В ИЗОГНУТОМ КОРНЕВОМ КАНАЛЕ ПРИ ПОВТОРНОМ ЭНДОДОНТИЧЕСКОМ ЛЕЧЕНИИ ЗУБОВ, РАНЕЕ ОБТУРИРОВАННЫХ РЕЗОРЦИН-ФОРМАЛИНОВЫМ МЕТОДОМ
Создание ступенчатого уступа при эндодонтическом лечении является ятрогенным осложнением. Под уступом понимают искусственно сформированное отклонения от естественной траектории корневого канала без сообщения с периодонто...