INFLUENCE OF POLYPHENOL EXTRACT, EXTRACTED FROM THE PLANT QUICE (CYDONIA OBLONG), ON THE mitoKATP-CHANNEL OF THE RAT’S LIVER
Journal Title: International scientific journal Science and Innovation - Year 2025, Vol 4, Issue 3
Abstract
In this article, the effect of PF-4 polyphenol extracts isolated from quince (Сydonia oblong) on the ATP-dependent potassium channel in rat liver mitochondria was studied. In the experiments, PF-4 polyphenol extracts (5 μg/ml, 10 μg/ml, 15 μg/ml, 20 μg/ml) activated the ATP-inhibited mitoKATP channel. The obtained results make it possible to create drugs with membrane-active action of PF-4 polyphenol extract in the future.
Authors and Affiliations
Soliyev N. N. , Abdullayeva G. T. , Asrarov M. I. , Madrakhimova S. D.
Keywords
Related Articles
- EP ID EP763149
- DOI 10.5281/zenodo.15148322
- Views 13
- Downloads 0
THE ROLE OF OUTSIDE THE CLASSROOM ACTIVITIES IN DIRECTING STUDENTS TO PROFESSIONS
This article analyzes the role of extracurricular activities in guiding schoolchildren to a profession, and in this process the teacher's pedagogical skills, knowledge and skills related to choosing a profession, as well...
TREATMENT OF PATIENTS WITH CUTANEOUS LEISCHMANIASIS IN THE REPUBLIC OF UZBEKISTAN
Skin leishmaniasis (Pendian ulcer, cutaneous leishmaniasis of the Old World - Borovsky's disease, cutaneous leishmaniasis of the New World, chancre of the Sahara, Biskra's bud, oriental ulcer, uglevik, yearling, Sart dis...
INTELLIGENT CALCULATION OF THE NUMBER OF REVOLUTIONS OF PARTICLES DURING CYCLONE DUST-AIR LAYER
The aim of the study is to develop a method for calculating the number of revolutions of accelerated motion of a particle in a turbulent dust-gas flow in the field of centrifugal forces of the cyclone apparatus. The mode...
CURRENT STATE OF SURGICAL TREATMENT OF GLIAL BRAIN TUMORS
Gliomas are one of the most common primary tumors of the central nervous system, and surgery remains the mainstay of treatment for gliomas of any grade. In this study, based on the introduction of gliomas, we review new...
TEACHER CAREER STRUCTURE REFORMS IN UZBEKISTAN: THE CURRENT CHALLENGES AND LESSONS LEARNED FROM TOP-PERFORMING EDUCATION SYSTEMS
The greater need than ever for well-prepared teachers with a strong subject knowledge, instructional and ICT skills has exacerbated during and after COVID-19 pandemic all around the world. Policymakers have understood cl...